1z62
From Proteopedia
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[[Image:1z62.png|left|200px]] | [[Image:1z62.png|left|200px]] | ||
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===Indirubin-3'-aminooxy-acetate inhibits glycogen phosphorylase by binding at the inhibitor and the allosteric site. Broad specificities of the two sites=== | ===Indirubin-3'-aminooxy-acetate inhibits glycogen phosphorylase by binding at the inhibitor and the allosteric site. Broad specificities of the two sites=== | ||
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{{ABSTRACT_PUBMED_15153119}} | {{ABSTRACT_PUBMED_15153119}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[1z62]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z62 OCA]. | + | [[1z62]] is a 1 chain structure of [[Glycogen Phosphorylase]] with sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z62 OCA]. |
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| + | ==See Also== | ||
| + | *[[Glycogen Phosphorylase|Glycogen Phosphorylase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:015153119</ref><ref group="xtra">PMID:009384557</ref><references group="xtra"/> |
[[Category: Oryctolagus cuniculus]] | [[Category: Oryctolagus cuniculus]] | ||
[[Category: Phosphorylase]] | [[Category: Phosphorylase]] | ||
Revision as of 10:46, 26 July 2012
Contents |
Indirubin-3'-aminooxy-acetate inhibits glycogen phosphorylase by binding at the inhibitor and the allosteric site. Broad specificities of the two sites
Template:ABSTRACT PUBMED 15153119
About this Structure
1z62 is a 1 chain structure of Glycogen Phosphorylase with sequence from Oryctolagus cuniculus. Full crystallographic information is available from OCA.
See Also
Reference
- Kosmopoulou MN, Leonidas DD, Chrysina ED, Bischler N, Eisenbrand G, Sakarellos CE, Pauptit R, Oikonomakos NG. Binding of the potential antitumour agent indirubin-5-sulphonate at the inhibitor site of rabbit muscle glycogen phosphorylase b. Comparison with ligand binding to pCDK2-cyclin A complex. Eur J Biochem. 2004 Jun;271(11):2280-90. PMID:15153119 doi:10.1111/j.1432-1033.2004.04173.x
- Zographos SE, Oikonomakos NG, Tsitsanou KE, Leonidas DD, Chrysina ED, Skamnaki VT, Bischoff H, Goldmann S, Watson KA, Johnson LN. The structure of glycogen phosphorylase b with an alkyldihydropyridine-dicarboxylic acid compound, a novel and potent inhibitor. Structure. 1997 Nov 15;5(11):1413-25. PMID:9384557
