3f8j
From Proteopedia
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Revision as of 19:29, 14 March 2011
Mouse UHRF1 SRA domain bound with hemi-methylated CpG, crystal structure in space group C222(1)
Template:ABSTRACT PUBMED 19077538
About this Structure
3f8j is a 3 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.
Reference
- Hashimoto H, Horton JR, Zhang X, Cheng X. UHRF1, a modular multi-domain protein, regulates replication-coupled crosstalk between DNA methylation and histone modifications. Epigenetics. 2009 Jan 10;4(1). PMID:19077538
- Hashimoto H, Horton JR, Zhang X, Bostick M, Jacobsen SE, Cheng X. The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix. Nature. 2008 Oct 9;455(7214):826-9. Epub 2008 Sep 3. PMID:18772888 doi:10.1038/nature07280
Categories: Mus musculus | Cheng, X. | Hashimoto, H. | Horton, J R. | Zhang, X. | 5-methylcytosine | Base flipping | Cell cycle | Cpg methylation | Developmental protein | Dna damage | Dna repair | Dna-binding | Ligase | Ligase/dna complex | Metal-binding | Nucleus | Phosphoprotein | Sra | Transcription | Transcription regulation | Ubl conjugation | Ubl conjugation pathway | Uhrf1 | Zinc | Zinc-finger
