This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2gkl
From Proteopedia
(Difference between revisions)
m (Protected "2gkl" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
[[Image:2gkl.png|left|200px]] | [[Image:2gkl.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_2gkl", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_2gkl| PDB=2gkl | SCENE= }} | {{STRUCTURE_2gkl| PDB=2gkl | SCENE= }} | ||
===Crystal structure of the zinc carbapenemase CPHA in complex with the inhibitor pyridine-2,4-dicarboxylate=== | ===Crystal structure of the zinc carbapenemase CPHA in complex with the inhibitor pyridine-2,4-dicarboxylate=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_17307979}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 17307979 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_17307979}} | {{ABSTRACT_PUBMED_17307979}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[2gkl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aeromonas_hydrophila Aeromonas hydrophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GKL OCA]. | + | [[2gkl]] is a 1 chain structure of [[Beta-lactamase]] with sequence from [http://en.wikipedia.org/wiki/Aeromonas_hydrophila Aeromonas hydrophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GKL OCA]. |
| + | |||
| + | ==See Also== | ||
| + | *[[Beta-lactamase|Beta-lactamase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017307979</ref><ref group="xtra">PMID:015588826</ref><ref group="xtra">PMID:015215079</ref><ref group="xtra">PMID:007588620</ref><references group="xtra"/> |
[[Category: Aeromonas hydrophila]] | [[Category: Aeromonas hydrophila]] | ||
[[Category: Beta-lactamase]] | [[Category: Beta-lactamase]] | ||
Revision as of 21:41, 26 July 2012
Contents |
Crystal structure of the zinc carbapenemase CPHA in complex with the inhibitor pyridine-2,4-dicarboxylate
Template:ABSTRACT PUBMED 17307979
About this Structure
2gkl is a 1 chain structure of Beta-lactamase with sequence from Aeromonas hydrophila. Full crystallographic information is available from OCA.
See Also
Reference
- Horsfall LE, Garau G, Lienard BM, Dideberg O, Schofield CJ, Frere JM, Galleni M. Competitive inhibitors of the CphA metallo-beta-lactamase from Aeromonas hydrophila. Antimicrob Agents Chemother. 2007 Jun;51(6):2136-42. Epub 2007 Feb 16. PMID:17307979 doi:10.1128/AAC.00866-06
- Garau G, Bebrone C, Anne C, Galleni M, Frere JM, Dideberg O. A metallo-beta-lactamase enzyme in action: crystal structures of the monozinc carbapenemase CphA and its complex with biapenem. J Mol Biol. 2005 Jan 28;345(4):785-95. PMID:15588826 doi:http://dx.doi.org/10.1016/j.jmb.2004.10.070
- Garau G, Garcia-Saez I, Bebrone C, Anne C, Mercuri P, Galleni M, Frere JM, Dideberg O. Update of the standard numbering scheme for class B beta-lactamases. Antimicrob Agents Chemother. 2004 Jul;48(7):2347-9. PMID:15215079 doi:http://dx.doi.org/10.1128/AAC.48.7.2347-2349.2004
- Carfi A, Pares S, Duee E, Galleni M, Duez C, Frere JM, Dideberg O. The 3-D structure of a zinc metallo-beta-lactamase from Bacillus cereus reveals a new type of protein fold. EMBO J. 1995 Oct 16;14(20):4914-21. PMID:7588620
