1h01
From Proteopedia
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:012941311</ref><ref group="xtra">PMID:008917641</ref><references group="xtra"/> |
| + | [[Category: Cyclin-dependent kinase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Non-specific serine/threonine protein kinase]] | ||
[[Category: Breault, G A.]] | [[Category: Breault, G A.]] | ||
[[Category: Ellston, R P.A.]] | [[Category: Ellston, R P.A.]] | ||
Revision as of 07:37, 30 October 2011
Contents |
CDK2 IN COMPLEX WITH A DISUBSTITUTED 2, 4-BIS ANILINO PYRIMIDINE CDK4 INHIBITOR
Template:ABSTRACT PUBMED 12941311
About this Structure
1h01 is a 1 chain structure of Cell Division Protein Kinase 2 with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Beattie JF, Breault GA, Ellston RP, Green S, Jewsbury PJ, Midgley CJ, Naven RT, Minshull CA, Pauptit RA, Tucker JA, Pease JE. Cyclin-dependent kinase 4 inhibitors as a treatment for cancer. Part 1: identification and optimisation of substituted 4,6-bis anilino pyrimidines. Bioorg Med Chem Lett. 2003 Sep 15;13(18):2955-60. PMID:12941311
- Schulze-Gahmen U, De Bondt HL, Kim SH. High-resolution crystal structures of human cyclin-dependent kinase 2 with and without ATP: bound waters and natural ligand as guides for inhibitor design. J Med Chem. 1996 Nov 8;39(23):4540-6. PMID:8917641 doi:10.1021/jm960402a
