1h3c

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[[Image:1h3c.png|left|200px]]
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{{STRUCTURE_1h3c| PDB=1h3c | SCENE= }}
{{STRUCTURE_1h3c| PDB=1h3c | SCENE= }}
===STRUCTURES OF HUMAN OXIDOSQUALENE CYCLASE INHIBITORS BOUND TO A HOMOLGOUS ENZYME===
===STRUCTURES OF HUMAN OXIDOSQUALENE CYCLASE INHIBITORS BOUND TO A HOMOLGOUS ENZYME===
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==Reference==
==Reference==
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<ref group="xtra">PMID:12747780</ref><ref group="xtra">PMID:12031670</ref><ref group="xtra">PMID:9931258</ref><ref group="xtra">PMID:9295270</ref><ref group="xtra">PMID:9162756</ref><references group="xtra"/>
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<ref group="xtra">PMID:012747780</ref><ref group="xtra">PMID:012031670</ref><ref group="xtra">PMID:009931258</ref><references group="xtra"/>
[[Category: Alicyclobacillus acidocaldarius]]
[[Category: Alicyclobacillus acidocaldarius]]
[[Category: Aebi, J D.]]
[[Category: Aebi, J D.]]

Revision as of 09:35, 16 January 2013

Template:STRUCTURE 1h3c

STRUCTURES OF HUMAN OXIDOSQUALENE CYCLASE INHIBITORS BOUND TO A HOMOLGOUS ENZYME

Template:ABSTRACT PUBMED 12747780

About this Structure

1h3c is a 3 chain structure with sequence from Alicyclobacillus acidocaldarius. Full crystallographic information is available from OCA.

Reference

  • Lenhart A, Reinert DJ, Aebi JD, Dehmlow H, Morand OH, Schulz GE. Binding structures and potencies of oxidosqualene cyclase inhibitors with the homologous squalene-hopene cyclase. J Med Chem. 2003 May 22;46(11):2083-92. PMID:12747780 doi:http://dx.doi.org/10.1021/jm0211218
  • Lenhart A, Weihofen WA, Pleschke AE, Schulz GE. Crystal structure of a squalene cyclase in complex with the potential anticholesteremic drug Ro48-8071. Chem Biol. 2002 May;9(5):639-45. PMID:12031670
  • Wendt KU, Lenhart A, Schulz GE. The structure of the membrane protein squalene-hopene cyclase at 2.0 A resolution. J Mol Biol. 1999 Feb 12;286(1):175-87. PMID:9931258 doi:http://dx.doi.org/10.1006/jmbi.1998.2470

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