3c7p

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[[Image:3c7p.png|left|200px]]
[[Image:3c7p.png|left|200px]]
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{{STRUCTURE_3c7p| PDB=3c7p | SCENE= }}
{{STRUCTURE_3c7p| PDB=3c7p | SCENE= }}
===Crystal structure of human carbonic anhydrase II in complex with STX237===
===Crystal structure of human carbonic anhydrase II in complex with STX237===
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{{ABSTRACT_PUBMED_18723489}}
{{ABSTRACT_PUBMED_18723489}}
==About this Structure==
==About this Structure==
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[[3c7p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C7P OCA].
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[[3c7p]] is a 1 chain structure of [[Carbonic anhydrase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C7P OCA].
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==See Also==
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*[[Carbonic anhydrase|Carbonic anhydrase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:18723489</ref><ref group="xtra">PMID:17181151</ref><references group="xtra"/>
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<ref group="xtra">PMID:018723489</ref><ref group="xtra">PMID:017181151</ref><references group="xtra"/>
[[Category: Carbonate dehydratase]]
[[Category: Carbonate dehydratase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Fiore, A Di.]]
[[Category: Fiore, A Di.]]
[[Category: Simone, G De.]]
[[Category: Simone, G De.]]
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[[Category: Acetylation]]
 
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[[Category: Cytoplasm]]
 
[[Category: Disease mutation]]
[[Category: Disease mutation]]
[[Category: Lyase]]
[[Category: Lyase]]
[[Category: Metal-binding]]
[[Category: Metal-binding]]
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[[Category: Polymorphism]]
 
[[Category: Protein-inhibitor complex]]
[[Category: Protein-inhibitor complex]]
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[[Category: Zinc]]
 

Revision as of 21:44, 26 July 2012

Template:STRUCTURE 3c7p

Contents

Crystal structure of human carbonic anhydrase II in complex with STX237

Template:ABSTRACT PUBMED 18723489

About this Structure

3c7p is a 1 chain structure of Carbonic anhydrase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Woo LW, Fischer DS, Sharland CM, Trusselle M, Foster PA, Chander SK, Di Fiore A, Supuran CT, De Simone G, Purohit A, Reed MJ, Potter BV. Anticancer steroid sulfatase inhibitors: synthesis of a potent fluorinated second-generation agent, in vitro and in vivo activities, molecular modeling, and protein crystallography. Mol Cancer Ther. 2008 Aug;7(8):2435-44. PMID:18723489 doi:7/8/2435
  • Leese MP, Leblond B, Smith A, Newman SP, Di Fiore A, De Simone G, Supuran CT, Purohit A, Reed MJ, Potter BV. 2-substituted estradiol bis-sulfamates, multitargeted antitumor agents: synthesis, in vitro SAR, protein crystallography, and in vivo activity. J Med Chem. 2006 Dec 28;49(26):7683-96. PMID:17181151 doi:10.1021/jm060705x

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