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1w3c

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Revision as of 21:11, 14 March 2011

Image:1w3c.png

Template:STRUCTURE 1w3c

CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS3 PROTEASE IN COMPLEX WITH A PEPTIDOMIMETIC INHIBITOR

Template:ABSTRACT PUBMED 15588076

About this Structure

1w3c is a 4 chain structure with sequence from Viruses. Full crystallographic information is available from OCA.

Reference

  • Ontoria JM, Di Marco S, Conte I, Di Francesco ME, Gardelli C, Koch U, Matassa VG, Poma M, Steinkuhler C, Volpari C, Harper S. The design and enzyme-bound crystal structure of indoline based peptidomimetic inhibitors of hepatitis C virus NS3 protease. J Med Chem. 2004 Dec 16;47(26):6443-6. PMID:15588076 doi:10.1021/jm049435d
  • Di Marco S, Rizzi M, Volpari C, Walsh MA, Narjes F, Colarusso S, De Francesco R, Matassa VG, Sollazzo M. Inhibition of the hepatitis C virus NS3/4A protease. The crystal structures of two protease-inhibitor complexes. J Biol Chem. 2000 Mar 10;275(10):7152-7. PMID:10702283

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