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3jz2
From Proteopedia
m (Protected "3jz2" [edit=sysop:move=sysop]) |
Revision as of 21:19, 14 March 2011
Crystal structure of human thrombin mutant N143P in E* form
Template:ABSTRACT PUBMED 19846563
About this Structure
3jz2 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Niu W, Chen Z, Bush-Pelc LA, Bah A, Gandhi PS, Di Cera E. Mutant N143P reveals how Na+ activates thrombin. J Biol Chem. 2009 Dec 25;284(52):36175-85. Epub 2009 Oct 21. PMID:19846563 doi:10.1074/jbc.M109.069500
- Gandhi PS, Chen Z, Mathews FS, Di Cera E. Structural identification of the pathway of long-range communication in an allosteric enzyme. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):1832-7. Epub 2008 Feb 4. PMID:18250335
- Pineda AO, Carrell CJ, Bush LA, Prasad S, Caccia S, Chen ZW, Mathews FS, Di Cera E. Molecular dissection of Na+ binding to thrombin. J Biol Chem. 2004 Jul 23;279(30):31842-53. Epub 2004 May 19. PMID:15152000 doi:http://dx.doi.org/10.1074/jbc.M401756200
Categories: Homo sapiens | Thrombin | Bah, A. | Bush-Pelc, L A. | Cera, E Di. | Chen, Z. | Gandhi, P S. | Niu, W. | Acute phase | Blood coagulation | Calcium | Cleavage on pair of basic residue | Disease mutation | Disulfide bond | Gamma-carboxyglutamic acid | Glycoprotein | Hydrolase | Kringle | Pharmaceutical | Polymorphism | Protease | Secreted | Serine protease | Zymogen
