This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2po5
From Proteopedia
(Difference between revisions)
m (Protected "2po5" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
[[Image:2po5.png|left|200px]] | [[Image:2po5.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_2po5", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_2po5| PDB=2po5 | SCENE= }} | {{STRUCTURE_2po5| PDB=2po5 | SCENE= }} | ||
===Crystal structure of human ferrochelatase mutant with His 263 replaced by Cys=== | ===Crystal structure of human ferrochelatase mutant with His 263 replaced by Cys=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_17567154}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 17567154 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_17567154}} | {{ABSTRACT_PUBMED_17567154}} | ||
==About this Structure== | ==About this Structure== | ||
[[2po5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PO5 OCA]. | [[2po5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PO5 OCA]. | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Ferrochelatase|Ferrochelatase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017567154</ref><ref group="xtra">PMID:011175906</ref><ref group="xtra">PMID:010561552</ref><references group="xtra"/> |
[[Category: Ferrochelatase]] | [[Category: Ferrochelatase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| Line 38: | Line 30: | ||
[[Category: H263c]] | [[Category: H263c]] | ||
[[Category: Heme biosynthesis]] | [[Category: Heme biosynthesis]] | ||
| + | [[Category: Lyase]] | ||
[[Category: Mature length]] | [[Category: Mature length]] | ||
[[Category: Proteolytically processed mitochondrial inner membrane protein]] | [[Category: Proteolytically processed mitochondrial inner membrane protein]] | ||
[[Category: Protoheme]] | [[Category: Protoheme]] | ||
Revision as of 13:03, 30 January 2013
Contents |
Crystal structure of human ferrochelatase mutant with His 263 replaced by Cys
Template:ABSTRACT PUBMED 17567154
About this Structure
2po5 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Dailey HA, Wu CK, Horanyi P, Medlock AE, Najahi-Missaoui W, Burden AE, Dailey TA, Rose J. Altered orientation of active site residues in variants of human ferrochelatase. Evidence for a hydrogen bond network involved in catalysis. Biochemistry. 2007 Jul 10;46(27):7973-9. Epub 2007 Jun 14. PMID:17567154 doi:10.1021/bi700151f
- Wu CK, Dailey HA, Rose JP, Burden A, Sellers VM, Wang BC. The 2.0 A structure of human ferrochelatase, the terminal enzyme of heme biosynthesis. Nat Struct Biol. 2001 Feb;8(2):156-60. PMID:11175906 doi:10.1038/84152
- Burden AE, Wu C, Dailey TA, Busch JL, Dhawan IK, Rose JP, Wang B, Dailey HA. Human ferrochelatase: crystallization, characterization of the [2Fe-2S] cluster and determination that the enzyme is a homodimer. Biochim Biophys Acta. 1999 Nov 16;1435(1-2):191-7. PMID:10561552
Categories: Ferrochelatase | Homo sapiens | Burden, A. | Dailey, H A. | Dailey, T A. | Horanyi, P. | Medlock, A E. | Najahi-Missaoui, A E.W. | Rose, J P. | Wu, C K. | Fe2s2 cluster | Ferro-lyase | H263c | Heme biosynthesis | Lyase | Mature length | Proteolytically processed mitochondrial inner membrane protein | Protoheme
