3pup
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:18973295</ref><ref group="xtra">PMID:19035373</ref><references group="xtra"/> | + | <ref group="xtra">PMID:21446733</ref><ref group="xtra">PMID:18973295</ref><ref group="xtra">PMID:19035373</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Essen, L O.]] | [[Category: Essen, L O.]] | ||
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[[Category: Kraling, K.]] | [[Category: Kraling, K.]] | ||
[[Category: Meggers, E.]] | [[Category: Meggers, E.]] | ||
| - | [[Category: Atp-binding]] | ||
| - | [[Category: Kinase]] | ||
| - | [[Category: Nucleotide-binding]] | ||
| - | [[Category: Phosphoprotein]] | ||
| - | [[Category: Ruthenium glycogen synthase kinase picomolar]] | ||
| - | [[Category: Serine/threonine-protein kinase]] | ||
| - | [[Category: Transferase]] | ||
| - | [[Category: Wnt signaling pathway]] | ||
Revision as of 09:45, 21 April 2011
Structure of Glycogen Synthase Kinase 3 beta (GSK3B) in complex with a ruthenium octasporine ligand (OS1)
Template:ABSTRACT PUBMED 21446733
About this Structure
3pup is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Feng L, Geisselbrecht Y, Blanck S, Wilbuer A, Atilla-Gokcumen GE, Filippakopoulos P, Kraling K, Celik MA, Harms K, Maksimoska J, Marmorstein R, Frenking G, Knapp S, Essen LO, Meggers E. Structurally Sophisticated Octahedral Metal Complexes as Highly Selective Protein Kinase Inhibitors. J Am Chem Soc. 2011 Apr 20;133(15):5976-5986. Epub 2011 Mar 29. PMID:21446733 doi:10.1021/ja1112996
- Maksimoska J, Feng L, Harms K, Yi C, Kissil J, Marmorstein R, Meggers E. Targeting large kinase active site with rigid, bulky octahedral ruthenium complexes. J Am Chem Soc. 2008 Nov 26;130(47):15764-5. PMID:18973295 doi:10.1021/ja805555a
- Atilla-Gokcumen GE, Pagano N, Streu C, Maksimoska J, Filippakopoulos P, Knapp S, Meggers E. Extremely tight binding of a ruthenium complex to glycogen synthase kinase 3. Chembiochem. 2008 Dec 15;9(18):2933-6. PMID:19035373 doi:10.1002/cbic.200800489
