1e0f
From Proteopedia
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{{STRUCTURE_1e0f| PDB=1e0f | SCENE= }} | {{STRUCTURE_1e0f| PDB=1e0f | SCENE= }} | ||
===CRYSTAL STRUCTURE OF THE HUMAN ALPHA-THROMBIN-HAEMADIN COMPLEX: AN EXOSITE II-BINDING INHIBITOR=== | ===CRYSTAL STRUCTURE OF THE HUMAN ALPHA-THROMBIN-HAEMADIN COMPLEX: AN EXOSITE II-BINDING INHIBITOR=== | ||
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{{ABSTRACT_PUBMED_11060016}} | {{ABSTRACT_PUBMED_11060016}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[1e0f]] is a 9 chain structure with sequence from [http://en.wikipedia.org/wiki/Haemadipsa_sylvestris Haemadipsa sylvestris] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E0F OCA]. | + | [[1e0f]] is a 9 chain structure of [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Haemadipsa_sylvestris Haemadipsa sylvestris] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E0F OCA]. |
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| + | ==See Also== | ||
| + | *[[Thrombin|Thrombin]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:011060016</ref><ref group="xtra">PMID:008473305</ref><ref group="xtra">PMID:001304349</ref><ref group="xtra">PMID:016673263</ref><references group="xtra"/> |
[[Category: Haemadipsa sylvestris]] | [[Category: Haemadipsa sylvestris]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Pereira, P.]] | [[Category: Pereira, P.]] | ||
[[Category: Richardson, J L.]] | [[Category: Richardson, J L.]] | ||
| + | [[Category: Coagulation-crystal structure-heparin-b complex]] | ||
[[Category: Coagulation/crystal structure/heparin-b]] | [[Category: Coagulation/crystal structure/heparin-b]] | ||
[[Category: Coagulation/crystal structure/heparin-binding site/ hirudin/thrombin inhibitor]] | [[Category: Coagulation/crystal structure/heparin-binding site/ hirudin/thrombin inhibitor]] | ||
Revision as of 01:17, 26 July 2012
Contents |
CRYSTAL STRUCTURE OF THE HUMAN ALPHA-THROMBIN-HAEMADIN COMPLEX: AN EXOSITE II-BINDING INHIBITOR
Template:ABSTRACT PUBMED 11060016
About this Structure
1e0f is a 9 chain structure of Thrombin with sequence from Haemadipsa sylvestris and Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Richardson JL, Kroger B, Hoeffken W, Sadler JE, Pereira P, Huber R, Bode W, Fuentes-Prior P. Crystal structure of the human alpha-thrombin-haemadin complex: an exosite II-binding inhibitor. EMBO J. 2000 Nov 1;19(21):5650-60. PMID:11060016 doi:10.1093/emboj/19.21.5650
- Strube KH, Kroger B, Bialojan S, Otte M, Dodt J. Isolation, sequence analysis, and cloning of haemadin. An anticoagulant peptide from the Indian leech. J Biol Chem. 1993 Apr 25;268(12):8590-5. PMID:8473305
- Bode W, Turk D, Karshikov A. The refined 1.9-A X-ray crystal structure of D-Phe-Pro-Arg chloromethylketone-inhibited human alpha-thrombin: structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships. Protein Sci. 1992 Apr;1(4):426-71. PMID:1304349
- Bode W. The structure of thrombin: a janus-headed proteinase. Semin Thromb Hemost. 2006 Apr;32 Suppl 1:16-31. PMID:16673263 doi:10.1055/s-2006-939551
Categories: Haemadipsa sylvestris | Homo sapiens | Thrombin | Bode, W. | Fuentes-Prior, P. | Hoefken, W. | Huber, R. | Kroeger, B. | Pereira, P. | Richardson, J L. | Coagulation-crystal structure-heparin-b complex | Coagulation/crystal structure/heparin-b | Coagulation/crystal structure/heparin-binding site/ hirudin/thrombin inhibitor
