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2g4b

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Image:2g4b.png

Template:STRUCTURE 2g4b

Structure of U2AF65 variant with polyuridine tract

Template:ABSTRACT PUBMED 16818232

About this Structure

2g4b is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Sickmier EA, Frato KE, Shen H, Paranawithana SR, Green MR, Kielkopf CL. Structural basis for polypyrimidine tract recognition by the essential pre-mRNA splicing factor U2AF65. Mol Cell. 2006 Jul 7;23(1):49-59. PMID:16818232 doi:http://dx.doi.org/10.1016/j.molcel.2006.05.025
  • Sickmier EA, Frato KE, Kielkopf CL. Crystallization and preliminary X-ray analysis of a U2AF65 variant in complex with a polypyrimidine-tract analogue by use of protein engineering. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 May 1;62(Pt, 5):457-9. Epub 2006 Apr 12. PMID:16682775 doi:10.1107/S1744309106012504

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OCA

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