2j4g

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[[Image:2j4g.png|left|200px]]
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{{STRUCTURE_2j4g| PDB=2j4g | SCENE= }}
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===BACTEROIDES THETAIOTAOMICRON GH84 O-GLCNACASE IN COMPLEX WITH N-BUTYL-THIAZOLINE INHIBITOR===
===BACTEROIDES THETAIOTAOMICRON GH84 O-GLCNACASE IN COMPLEX WITH N-BUTYL-THIAZOLINE INHIBITOR===
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==Reference==
==Reference==
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<ref group="xtra">PMID:17227027</ref><ref group="xtra">PMID:16565725</ref><references group="xtra"/>
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<ref group="xtra">PMID:017227027</ref><ref group="xtra">PMID:016565725</ref><references group="xtra"/>
[[Category: Bacteroides thetaiotaomicron]]
[[Category: Bacteroides thetaiotaomicron]]
[[Category: Beta-N-acetylhexosaminidase]]
[[Category: Beta-N-acetylhexosaminidase]]

Revision as of 13:22, 30 January 2013

Template:STRUCTURE 2j4g

BACTEROIDES THETAIOTAOMICRON GH84 O-GLCNACASE IN COMPLEX WITH N-BUTYL-THIAZOLINE INHIBITOR

Template:ABSTRACT PUBMED 17227027

About this Structure

2j4g is a 2 chain structure with sequence from Bacteroides thetaiotaomicron. Full crystallographic information is available from OCA.

Reference

  • Whitworth GE, Macauley MS, Stubbs KA, Dennis RJ, Taylor EJ, Davies GJ, Greig IR, Vocadlo DJ. Analysis of PUGNAc and NAG-thiazoline as transition state analogues for human O-GlcNAcase: mechanistic and structural insights into inhibitor selectivity and transition state poise. J Am Chem Soc. 2007 Jan 24;129(3):635-44. PMID:17227027 doi:http://dx.doi.org/10.1021/ja065697o
  • Dennis RJ, Taylor EJ, Macauley MS, Stubbs KA, Turkenburg JP, Hart SJ, Black GN, Vocadlo DJ, Davies GJ. Structure and mechanism of a bacterial beta-glucosaminidase having O-GlcNAcase activity. Nat Struct Mol Biol. 2006 Apr;13(4):365-71. Epub 2006 Mar 26. PMID:16565725 doi:http://dx.doi.org/10.1038/nsmb1079

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