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2j4g
From Proteopedia
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[[Image:2j4g.png|left|200px]] | [[Image:2j4g.png|left|200px]] | ||
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{{STRUCTURE_2j4g| PDB=2j4g | SCENE= }} | {{STRUCTURE_2j4g| PDB=2j4g | SCENE= }} | ||
===BACTEROIDES THETAIOTAOMICRON GH84 O-GLCNACASE IN COMPLEX WITH N-BUTYL-THIAZOLINE INHIBITOR=== | ===BACTEROIDES THETAIOTAOMICRON GH84 O-GLCNACASE IN COMPLEX WITH N-BUTYL-THIAZOLINE INHIBITOR=== | ||
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==Reference== | ==Reference== | ||
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[[Category: Bacteroides thetaiotaomicron]] | [[Category: Bacteroides thetaiotaomicron]] | ||
[[Category: Beta-N-acetylhexosaminidase]] | [[Category: Beta-N-acetylhexosaminidase]] | ||
Revision as of 13:22, 30 January 2013
BACTEROIDES THETAIOTAOMICRON GH84 O-GLCNACASE IN COMPLEX WITH N-BUTYL-THIAZOLINE INHIBITOR
Template:ABSTRACT PUBMED 17227027
About this Structure
2j4g is a 2 chain structure with sequence from Bacteroides thetaiotaomicron. Full crystallographic information is available from OCA.
Reference
- Whitworth GE, Macauley MS, Stubbs KA, Dennis RJ, Taylor EJ, Davies GJ, Greig IR, Vocadlo DJ. Analysis of PUGNAc and NAG-thiazoline as transition state analogues for human O-GlcNAcase: mechanistic and structural insights into inhibitor selectivity and transition state poise. J Am Chem Soc. 2007 Jan 24;129(3):635-44. PMID:17227027 doi:http://dx.doi.org/10.1021/ja065697o
- Dennis RJ, Taylor EJ, Macauley MS, Stubbs KA, Turkenburg JP, Hart SJ, Black GN, Vocadlo DJ, Davies GJ. Structure and mechanism of a bacterial beta-glucosaminidase having O-GlcNAcase activity. Nat Struct Mol Biol. 2006 Apr;13(4):365-71. Epub 2006 Mar 26. PMID:16565725 doi:http://dx.doi.org/10.1038/nsmb1079
