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2cl5
From Proteopedia
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[[Image:2cl5.png|left|200px]] | [[Image:2cl5.png|left|200px]] | ||
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{{STRUCTURE_2cl5| PDB=2cl5 | SCENE= }} | {{STRUCTURE_2cl5| PDB=2cl5 | SCENE= }} | ||
===CATECHOL-O-METHYLTRANSFERASE IN COMPLEX WITH AN INHIBITOR=== | ===CATECHOL-O-METHYLTRANSFERASE IN COMPLEX WITH AN INHIBITOR=== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016618795</ref><ref group="xtra">PMID:016508109</ref><ref group="xtra">PMID:016698551</ref><references group="xtra"/> |
[[Category: Catechol O-methyltransferase]] | [[Category: Catechol O-methyltransferase]] | ||
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
Revision as of 12:17, 23 January 2013
CATECHOL-O-METHYLTRANSFERASE IN COMPLEX WITH AN INHIBITOR
Template:ABSTRACT PUBMED 16618795
About this Structure
2cl5 is a 2 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
Reference
- Palma PN, Rodrigues ML, Archer M, Bonifacio MJ, Loureiro AI, Learmonth DA, Carrondo MA, Soares-da-Silva P. Comparative study of ortho- and meta-nitrated inhibitors of catechol-O-methyltransferase: interactions with the active site and regioselectivity of O-methylation. Mol Pharmacol. 2006 Jul;70(1):143-53. Epub 2006 Apr 17. PMID:16618795 doi:10.1124/mol.106.023119
- Rodrigues ML, Bonifacio MJ, Soares-da-Silva P, Carrondo MA, Archer M. Crystallization and preliminary X-ray diffraction studies of a catechol-O-methyltransferase/inhibitor complex. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Jan 1;61(Pt, 1):118-20. Epub 2004 Dec 24. PMID:16508109 doi:10.1107/S1744309104031197
- Frey D, Braun O, Briand C, Vasak M, Grutter MG. Structure of the mammalian NOS regulator dimethylarginine dimethylaminohydrolase: A basis for the design of specific inhibitors. Structure. 2006 May;14(5):901-11. PMID:16698551 doi:http://dx.doi.org/10.1016/j.str.2006.03.006
Categories: Catechol O-methyltransferase | Rattus norvegicus | Archer, M. | Bonifacio, M J. | Carrondo, M A. | Learmonth, D A. | Loureiro, A I. | Palma, P N. | Rodrigues, M L. | Soares-Da-Silva, P. | Alternative initiation | Catechol-o-methyltransferase | Catecholamine metabolism | Comt inhibitor | Magnesium | Membrane | Metal-binding | Methyltransferase | Neurotransmitter degradation | Phosphorylation | Signal-anchor | Transferase | Transmembrane
