2rdk

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[[Image:2rdk.png|left|200px]]
[[Image:2rdk.png|left|200px]]
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{{STRUCTURE_2rdk| PDB=2rdk | SCENE= }}
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===Five site mutated Cyanovirin-N with Mannose dimer bound===
===Five site mutated Cyanovirin-N with Mannose dimer bound===
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==Reference==
==Reference==
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<ref group="xtra">PMID:18436959</ref><ref group="xtra">PMID:17636873</ref><references group="xtra"/>
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<ref group="xtra">PMID:018436959</ref><ref group="xtra">PMID:017636873</ref><references group="xtra"/>
[[Category: Nostoc ellipsosporum]]
[[Category: Nostoc ellipsosporum]]
[[Category: Fromme, P.]]
[[Category: Fromme, P.]]
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[[Category: Protein synthesis inhibitor]]
[[Category: Protein synthesis inhibitor]]
[[Category: Sugar binding protein]]
[[Category: Sugar binding protein]]
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[[Category: X-ray diffraction]]
 

Revision as of 13:08, 30 January 2013

Template:STRUCTURE 2rdk

Five site mutated Cyanovirin-N with Mannose dimer bound

Template:ABSTRACT PUBMED 18436959

About this Structure

2rdk is a 2 chain structure with sequence from Nostoc ellipsosporum. Full crystallographic information is available from OCA.

Reference

  • Fromme R, Katiliene Z, Fromme P, Ghirlanda G. Conformational gating of dimannose binding to the antiviral protein cyanovirin revealed from the crystal structure at 1.35 A resolution. Protein Sci. 2008 May;17(5):939-44. PMID:18436959 doi:17/5/939
  • Fromme R, Katiliene Z, Giomarelli B, Bogani F, Mc Mahon J, Mori T, Fromme P, Ghirlanda G. A monovalent mutant of cyanovirin-N provides insight into the role of multiple interactions with gp120 for antiviral activity. Biochemistry. 2007 Aug 14;46(32):9199-207. Epub 2007 Jul 18. PMID:17636873 doi:10.1021/bi700666m

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