3hk6
From Proteopedia
(Difference between revisions)
m (Protected "3hk6" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
[[Image:3hk6.png|left|200px]] | [[Image:3hk6.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_3hk6", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_3hk6| PDB=3hk6 | SCENE= }} | {{STRUCTURE_3hk6| PDB=3hk6 | SCENE= }} | ||
===Crystal structure of murine thrombin mutant W215A/E217A (two molecules in the asymmetric unit)=== | ===Crystal structure of murine thrombin mutant W215A/E217A (two molecules in the asymmetric unit)=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_19586901}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 19586901 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_19586901}} | {{ABSTRACT_PUBMED_19586901}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3hk6]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HK6 OCA]. | + | [[3hk6]] is a 4 chain structure of [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HK6 OCA]. |
| + | |||
| + | ==See Also== | ||
| + | *[[Thrombin|Thrombin]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019586901</ref><ref group="xtra">PMID:015252033</ref><references group="xtra"/> |
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Thrombin]] | [[Category: Thrombin]] | ||
| Line 32: | Line 24: | ||
[[Category: Acute phase]] | [[Category: Acute phase]] | ||
[[Category: Blood coagulation]] | [[Category: Blood coagulation]] | ||
| - | [[Category: Calcium]] | ||
[[Category: Cleavage on pair of basic residue]] | [[Category: Cleavage on pair of basic residue]] | ||
[[Category: Disulfide bond]] | [[Category: Disulfide bond]] | ||
Revision as of 19:08, 26 July 2012
Contents |
Crystal structure of murine thrombin mutant W215A/E217A (two molecules in the asymmetric unit)
Template:ABSTRACT PUBMED 19586901
About this Structure
3hk6 is a 4 chain structure of Thrombin with sequence from Mus musculus. Full crystallographic information is available from OCA.
See Also
Reference
- Gandhi PS, Page MJ, Chen Z, Bush-Pelc L, Di Cera E. Mechanism of the anticoagulant activity of thrombin mutant W215A/E217A. J Biol Chem. 2009 Sep 4;284(36):24098-105. Epub 2009 Jul 8. PMID:19586901 doi:10.1074/jbc.M109.025403
- Pineda AO, Chen ZW, Caccia S, Cantwell AM, Savvides SN, Waksman G, Mathews FS, Di Cera E. The anticoagulant thrombin mutant W215A/E217A has a collapsed primary specificity pocket. J Biol Chem. 2004 Sep 17;279(38):39824-8. Epub 2004 Jul 13. PMID:15252033 doi:http://dx.doi.org/10.1074/jbc.M407272200
