2o36

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Revision as of 23:35, 14 March 2011

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Template:STRUCTURE 2o36

Crystal structure of engineered thimet oligopeptidase with neurolysin specificity in neurotensin cleavage site

Template:ABSTRACT PUBMED 17251185

About this Structure

2o36 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Lim EJ, Sampath S, Coll-Rodriguez J, Schmidt J, Ray K, Rodgers DW. Swapping the substrate specificities of the neuropeptidases neurolysin and thimet oligopeptidase. J Biol Chem. 2007 Mar 30;282(13):9722-32. Epub 2007 Jan 24. PMID:17251185 doi:10.1074/jbc.M609897200
• Ray K, Hines CS, Coll-Rodriguez J, Rodgers DW. Crystal structure of human thimet oligopeptidase provides insight into substrate recognition, regulation, and localization. J Biol Chem. 2004 May 7;279(19):20480-9. Epub 2004 Mar 3. PMID:14998993 doi:10.1074/jbc.M400795200