2ati

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[[Image:2ati.png|left|200px]]
[[Image:2ati.png|left|200px]]
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{{STRUCTURE_2ati| PDB=2ati | SCENE= }}
{{STRUCTURE_2ati| PDB=2ati | SCENE= }}
===Glycogen Phosphorylase Inhibitors===
===Glycogen Phosphorylase Inhibitors===
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{{ABSTRACT_PUBMED_16190745}}
{{ABSTRACT_PUBMED_16190745}}
==About this Structure==
==About this Structure==
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[[2ati]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ATI OCA].
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[[2ati]] is a 2 chain structure of [[Glycogen Phosphorylase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ATI OCA].
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==See Also==
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*[[Glycogen Phosphorylase|Glycogen Phosphorylase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:16190745</ref><ref group="xtra">PMID:15987904</ref><ref group="xtra">PMID:10949035</ref><references group="xtra"/>
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<ref group="xtra">PMID:016190745</ref><ref group="xtra">PMID:015987904</ref><ref group="xtra">PMID:010949035</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Phosphorylase]]
[[Category: Phosphorylase]]

Revision as of 06:08, 26 July 2012

Image:2ati.png

Template:STRUCTURE 2ati

Contents

Glycogen Phosphorylase Inhibitors

Template:ABSTRACT PUBMED 16190745

About this Structure

2ati is a 2 chain structure of Glycogen Phosphorylase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Klabunde T, Wendt KU, Kadereit D, Brachvogel V, Burger HJ, Herling AW, Oikonomakos NG, Kosmopoulou MN, Schmoll D, Sarubbi E, von Roedern E, Schonafinger K, Defossa E. Acyl ureas as human liver glycogen phosphorylase inhibitors for the treatment of type 2 diabetes. J Med Chem. 2005 Oct 6;48(20):6178-93. PMID:16190745 doi:10.1021/jm049034y
  • Oikonomakos NG, Kosmopoulou MN, Chrysina ED, Leonidas DD, Kostas ID, Wendt KU, Klabunde T, Defossa E. Crystallographic studies on acyl ureas, a new class of glycogen phosphorylase inhibitors, as potential antidiabetic drugs. Protein Sci. 2005 Jul;14(7):1760-71. PMID:15987904 doi:14/7/1760
  • Rath VL, Ammirati M, LeMotte PK, Fennell KF, Mansour MN, Danley DE, Hynes TR, Schulte GK, Wasilko DJ, Pandit J. Activation of human liver glycogen phosphorylase by alteration of the secondary structure and packing of the catalytic core. Mol Cell. 2000 Jul;6(1):139-48. PMID:10949035

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