This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1v1k
From Proteopedia
m (Protected "1v1k" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
[[Image:1v1k.png|left|200px]] | [[Image:1v1k.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_1v1k", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_1v1k| PDB=1v1k | SCENE= }} | {{STRUCTURE_1v1k| PDB=1v1k | SCENE= }} | ||
===CDK2 IN COMPLEX WITH A DISUBSTITUTED 4, 6-BIS ANILINO PYRIMIDINE CDK4 INHIBITOR=== | ===CDK2 IN COMPLEX WITH A DISUBSTITUTED 4, 6-BIS ANILINO PYRIMIDINE CDK4 INHIBITOR=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_12941311}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 12941311 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_12941311}} | {{ABSTRACT_PUBMED_12941311}} | ||
| Line 22: | Line 11: | ||
==See Also== | ==See Also== | ||
| - | *[[Cell Division Protein Kinase 2]] | + | *[[Cell Division Protein Kinase 2|Cell Division Protein Kinase 2]] |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:012941311</ref><ref group="xtra">PMID:008917641</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
Revision as of 19:32, 25 July 2012
Contents |
CDK2 IN COMPLEX WITH A DISUBSTITUTED 4, 6-BIS ANILINO PYRIMIDINE CDK4 INHIBITOR
Template:ABSTRACT PUBMED 12941311
About this Structure
1v1k is a 1 chain structure of Cell Division Protein Kinase 2 with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 1h06. Full crystallographic information is available from OCA.
See Also
Reference
- Beattie JF, Breault GA, Ellston RP, Green S, Jewsbury PJ, Midgley CJ, Naven RT, Minshull CA, Pauptit RA, Tucker JA, Pease JE. Cyclin-dependent kinase 4 inhibitors as a treatment for cancer. Part 1: identification and optimisation of substituted 4,6-bis anilino pyrimidines. Bioorg Med Chem Lett. 2003 Sep 15;13(18):2955-60. PMID:12941311
- Schulze-Gahmen U, De Bondt HL, Kim SH. High-resolution crystal structures of human cyclin-dependent kinase 2 with and without ATP: bound waters and natural ligand as guides for inhibitor design. J Med Chem. 1996 Nov 8;39(23):4540-6. PMID:8917641 doi:10.1021/jm960402a
Categories: Homo sapiens | Non-specific serine/threonine protein kinase | Beattie, J F. | Breault, G A. | Ellston, R P.A. | Green, S. | Jewsbury, P J. | Midgley, C J. | Minshull, C A. | Naven, R T. | Pauptit, R A. | Pease, J E. | Tucker, J A. | Mitosis | Serine/threonine-protein kinase | Transferase
