2oph
From Proteopedia
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[[Image:2oph.png|left|200px]] | [[Image:2oph.png|left|200px]] | ||
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{{STRUCTURE_2oph| PDB=2oph | SCENE= }} | {{STRUCTURE_2oph| PDB=2oph | SCENE= }} | ||
===Human dipeptidyl peptidase IV in complex with an alpha amino acid inhibitor=== | ===Human dipeptidyl peptidase IV in complex with an alpha amino acid inhibitor=== | ||
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{{ABSTRACT_PUBMED_17350841}} | {{ABSTRACT_PUBMED_17350841}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[2oph]] is a 2 chain structure of [[Dipeptidyl peptidase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OPH OCA]. | + | [[2oph]] is a 2 chain structure of [[Beta secretase]] and [[Dipeptidyl peptidase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OPH OCA]. |
==See Also== | ==See Also== | ||
| - | *[[Dipeptidyl peptidase]] | + | *[[Beta secretase|Beta secretase]] |
| + | *[[Dipeptidyl peptidase|Dipeptidyl peptidase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017350841</ref><references group="xtra"/> |
[[Category: Dipeptidyl-peptidase IV]] | [[Category: Dipeptidyl-peptidase IV]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Scapin, G.]] | [[Category: Scapin, G.]] | ||
[[Category: Weber, A E.]] | [[Category: Weber, A E.]] | ||
| + | [[Category: Alpha/beta]] | ||
| + | [[Category: Beta-propeller]] | ||
| + | [[Category: Dimer]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Selective inhibitor]] | ||
| + | [[Category: Type 2 diabetes]] | ||
Revision as of 02:28, 26 July 2012
Contents |
Human dipeptidyl peptidase IV in complex with an alpha amino acid inhibitor
Template:ABSTRACT PUBMED 17350841
About this Structure
2oph is a 2 chain structure of Beta secretase and Dipeptidyl peptidase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Duffy JL, Kirk BA, Wang L, Eiermann GJ, He H, Leiting B, Lyons KA, Patel RA, Patel SB, Petrov A, Scapin G, Wu JK, Thornberry NA, Weber AE. 4-aminophenylalanine and 4-aminocyclohexylalanine derivatives as potent, selective, and orally bioavailable inhibitors of dipeptidyl peptidase IV. Bioorg Med Chem Lett. 2007 May 15;17(10):2879-85. Epub 2007 Feb 25. PMID:17350841 doi:10.1016/j.bmcl.2007.02.066
