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3q0q
From Proteopedia
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{{STRUCTURE_3q0q| PDB=3q0q | SCENE= }} | {{STRUCTURE_3q0q| PDB=3q0q | SCENE= }} | ||
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===Crystal structure of the PUMILIO-homology domain from Human PUMILIO2 in complex with p38alpha NREa=== | ===Crystal structure of the PUMILIO-homology domain from Human PUMILIO2 in complex with p38alpha NREa=== | ||
| + | {{ABSTRACT_PUBMED_021397187}} | ||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/PUM2_HUMAN PUM2_HUMAN]] Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. Its interactions and tissue specificity suggest that it may be required to support proliferation and self-renewal of stem cells by regulating the translation of key transcripts. | ||
==About this Structure== | ==About this Structure== | ||
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[[Category: Hall, T M.T.]] | [[Category: Hall, T M.T.]] | ||
[[Category: Lu, G.]] | [[Category: Lu, G.]] | ||
| + | [[Category: Gene regulation]] | ||
| + | [[Category: Puf]] | ||
| + | [[Category: Pumilio-homolgy domain]] | ||
| + | [[Category: Rna binding]] | ||
| + | [[Category: Rna binding protein-rna complex]] | ||
Revision as of 08:14, 8 May 2013
Crystal structure of the PUMILIO-homology domain from Human PUMILIO2 in complex with p38alpha NREa
Template:ABSTRACT PUBMED 021397187
Function
[PUM2_HUMAN] Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. Its interactions and tissue specificity suggest that it may be required to support proliferation and self-renewal of stem cells by regulating the translation of key transcripts.
About this Structure
3q0q is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
