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3okv

From Proteopedia

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m (Protected "3okv" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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[[Image:3okv.jpg|left|200px]]
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The entry 3okv is ON HOLD until Paper Publication
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{{STRUCTURE_3okv| PDB=3okv | SCENE= }}
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Authors: Sippel, K.H., Stander, B.A., Robbins, A.H., Tu, C.K., Agbandje-McKenna, M., Silverman, D.N., Joubert, A.M., McKenna, R.
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===Human Carbonic Anhydrase II A65S, N67Q (CA IX mimic) bound with 2-Ethylestrone 3-O-sulfamate===
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Description: Human Carbonic Anhydrase II A65S, N67Q (CA IX mimic) bound with 2-Ethylestrone 3-O-sulfamate
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{{ABSTRACT_PUBMED_20297840}}
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==About this Structure==
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[[3okv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OKV OCA].
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==Reference==
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<ref group="xtra">PMID:020297840</ref><ref group="xtra">PMID:019170619</ref><references group="xtra"/>
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[[Category: Carbonate dehydratase]]
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[[Category: Homo sapiens]]
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[[Category: Agbandje-McKenna, M.]]
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[[Category: Joubert, A M.]]
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[[Category: McKenna, R.]]
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[[Category: Robbins, A H.]]
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[[Category: Silverman, D N.]]
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[[Category: Sippel, K H.]]
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[[Category: Stander, B A.]]
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[[Category: Tu, C K.]]
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[[Category: Lyase]]
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[[Category: Mixes alpha/beta fold]]
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[[Category: Reversible hydration of carbon dioxide to bicarbonate]]

Revision as of 18:58, 6 July 2011

Template:STRUCTURE 3okv

Human Carbonic Anhydrase II A65S, N67Q (CA IX mimic) bound with 2-Ethylestrone 3-O-sulfamate

Template:ABSTRACT PUBMED 20297840

About this Structure

3okv is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Cozier GE, Leese MP, Lloyd MD, Baker MD, Thiyagarajan N, Acharya KR, Potter BV. Structures of Human Carbonic Anhydrase II/Inhibitor Complexes Reveal a Second Binding Site for Steroidal and Nonsteroidal Inhibitors (,). Biochemistry. 2010 Mar 29. PMID:20297840 doi:10.1021/bi902178w
  • Genis C, Sippel KH, Case N, Cao W, Avvaru BS, Tartaglia LJ, Govindasamy L, Tu C, Agbandje-McKenna M, Silverman DN, Rosser CJ, McKenna R. Design of a Carbonic Anhydrase IX Active-Site Mimic To Screen Inhibitors for Possible Anticancer Properties (dagger) (double dagger). Biochemistry. 2009 Jan 26. PMID:19170619 doi:10.1021/bi802035f

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