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3q9c
From Proteopedia
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{{STRUCTURE_3q9c| PDB=3q9c | SCENE= }} | {{STRUCTURE_3q9c| PDB=3q9c | SCENE= }} | ||
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===Crystal Structure of H159A APAH complexed with N8-acetylspermidine=== | ===Crystal Structure of H159A APAH complexed with N8-acetylspermidine=== | ||
| + | {{ABSTRACT_PUBMED_21268586}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/APHA_MYCRA APHA_MYCRA]] Acts on many types of acetylpolyamines. Has high affinity towards acetylputrescine, acetylcadaverine, acetylspermidine, and acetylspermine. Acts on L-Lys-(epsilon-acetyl)-coumarin, but has very low activity towards acetylated peptides. | |
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==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:021268586</ref><references group="xtra"/><references/> |
[[Category: Mycoplana ramosa]] | [[Category: Mycoplana ramosa]] | ||
[[Category: Christianson, D W.]] | [[Category: Christianson, D W.]] | ||
[[Category: Lombardi, P M.]] | [[Category: Lombardi, P M.]] | ||
| + | [[Category: Arginase fold]] | ||
| + | [[Category: Deacetylase]] | ||
| + | [[Category: Hdac]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Polyamine]] | ||
Revision as of 08:22, 8 May 2013
Contents |
Crystal Structure of H159A APAH complexed with N8-acetylspermidine
Template:ABSTRACT PUBMED 21268586
Function
[APHA_MYCRA] Acts on many types of acetylpolyamines. Has high affinity towards acetylputrescine, acetylcadaverine, acetylspermidine, and acetylspermine. Acts on L-Lys-(epsilon-acetyl)-coumarin, but has very low activity towards acetylated peptides.
About this Structure
3q9c is a 12 chain structure with sequence from Mycoplana ramosa. Full crystallographic information is available from OCA.
Reference
- Lombardi PM, Angell HD, Whittington DA, Flynn EF, Rajashankar KR, Christianson DW. Structure of Prokaryotic Polyamine Deacetylase Reveals Evolutionary Functional Relationships with Eukaryotic Histone Deacetylases . Biochemistry. 2011 Jan 26. PMID:21268586 doi:10.1021/bi101859k
