3qgb

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:3qgb.png|left|200px]]
 
- 
-
<!--
 
-
The line below this paragraph, containing "STRUCTURE_3qgb", creates the "Structure Box" on the page.
 
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
 
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
 
-
or leave the SCENE parameter empty for the default display.
 
-
-->
 
{{STRUCTURE_3qgb| PDB=3qgb | SCENE= }}
{{STRUCTURE_3qgb| PDB=3qgb | SCENE= }}
- 
===Crystal structure of FBF-2 R288Y mutant in complex with gld-1 FBEa===
===Crystal structure of FBF-2 R288Y mutant in complex with gld-1 FBEa===
 +
{{ABSTRACT_PUBMED_21372189}}
-
 
+
==Function==
-
<!--
+
[[http://www.uniprot.org/uniprot/FBF2_CAEEL FBF2_CAEEL]] Involved in the control of stem cells and sex determination in the C.elegans hermaphrodite germline. May also play a role in the hermaphrodite germline proliferation and oogenesis. Binds specifically to the regulatory region of fem-3 3'-UTR and mediates the sperm/oocyte switch. Negatively regulates gld-3 expression possibly by directly binding to two sites within the gld-3 isoform B 3'-UTR.<ref>PMID:9393998</ref> <ref>PMID:15454534</ref>
-
The line below this paragraph, {{ABSTRACT_PUBMED_21372189}}, adds the Publication Abstract to the page
+
-
(as it appears on PubMed at http://www.pubmed.gov), where 21372189 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_21372189}}
+
==About this Structure==
==About this Structure==
Line 22: Line 10:
==Reference==
==Reference==
-
<ref group="xtra">PMID:21372189</ref><references group="xtra"/>
+
<ref group="xtra">PMID:021372189</ref><references group="xtra"/><references/>
[[Category: Caenorhabditis elegans]]
[[Category: Caenorhabditis elegans]]
[[Category: Gross, L.]]
[[Category: Gross, L.]]
Line 31: Line 19:
[[Category: Wang, Y.]]
[[Category: Wang, Y.]]
[[Category: Wickens, M.]]
[[Category: Wickens, M.]]
 +
[[Category: Base stacking]]
 +
[[Category: Fbf]]
 +
[[Category: Fem-3 binding factor]]
 +
[[Category: Puf]]
 +
[[Category: Rna binding protein-rna complex]]
 +
[[Category: Rna-binding specificity]]

Revision as of 08:09, 8 May 2013

Template:STRUCTURE 3qgb

Contents

Crystal structure of FBF-2 R288Y mutant in complex with gld-1 FBEa

Template:ABSTRACT PUBMED 21372189

Function

[FBF2_CAEEL] Involved in the control of stem cells and sex determination in the C.elegans hermaphrodite germline. May also play a role in the hermaphrodite germline proliferation and oogenesis. Binds specifically to the regulatory region of fem-3 3'-UTR and mediates the sperm/oocyte switch. Negatively regulates gld-3 expression possibly by directly binding to two sites within the gld-3 isoform B 3'-UTR.[1] [2]

About this Structure

3qgb is a 2 chain structure with sequence from Caenorhabditis elegans. Full crystallographic information is available from OCA.

Reference

  • Koh YY, Wang Y, Qiu C, Opperman L, Gross L, Tanaka Hall TM, Wickens M. Stacking interactions in PUF-RNA complexes. RNA. 2011 Apr;17(4):718-27. Epub 2011 Mar 3. PMID:21372189 doi:10.1261/rna.2540311
  1. Zhang B, Gallegos M, Puoti A, Durkin E, Fields S, Kimble J, Wickens MP. A conserved RNA-binding protein that regulates sexual fates in the C. elegans hermaphrodite germ line. Nature. 1997 Dec 4;390(6659):477-84. PMID:9393998 doi:10.1038/37297
  2. Eckmann CR, Crittenden SL, Suh N, Kimble J. GLD-3 and control of the mitosis/meiosis decision in the germline of Caenorhabditis elegans. Genetics. 2004 Sep;168(1):147-60. PMID:15454534 doi:10.1534/genetics.104.029264

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools