3qmh

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[[Image:3qmh.png|left|200px]]
 
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{{STRUCTURE_3qmh| PDB=3qmh | SCENE= }}
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===Structural Basis of Selective Binding of Non-Methylated CpG islands (DNA-TCGA) by the CXXC Domain of CFP1===
===Structural Basis of Selective Binding of Non-Methylated CpG islands (DNA-TCGA) by the CXXC Domain of CFP1===
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{{ABSTRACT_PUBMED_21407193}}
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==Function==
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[[http://www.uniprot.org/uniprot/CXXC1_HUMAN CXXC1_HUMAN]] Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG.<ref>PMID:21407193</ref>
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{{ABSTRACT_PUBMED_21407193}}
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==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:21407193</ref><references group="xtra"/>
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<ref group="xtra">PMID:021407193</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C H.]]
[[Category: Arrowsmith, C H.]]
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[[Category: Weigelt, J.]]
[[Category: Weigelt, J.]]
[[Category: Xu, C.]]
[[Category: Xu, C.]]
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[[Category: Dna binding]]
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[[Category: Dna binding protein-dna complex]]
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[[Category: Sgc]]
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[[Category: Structural genomics consortium]]

Revision as of 08:10, 8 May 2013

Template:STRUCTURE 3qmh

Contents

Structural Basis of Selective Binding of Non-Methylated CpG islands (DNA-TCGA) by the CXXC Domain of CFP1

Template:ABSTRACT PUBMED 21407193

Function

[CXXC1_HUMAN] Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG.[1]

About this Structure

3qmh is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Xu C, Bian C, Lam R, Dong A, Min J. The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain. Nat Commun. 2011 Mar;2:227. PMID:21407193 doi:10.1038/ncomms1237
  1. ↑ Xu C, Bian C, Lam R, Dong A, Min J. The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain. Nat Commun. 2011 Mar;2:227. PMID:21407193 doi:10.1038/ncomms1237

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OCA

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