2xnn
From Proteopedia
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{{STRUCTURE_2xnn| PDB=2xnn | SCENE= }} | {{STRUCTURE_2xnn| PDB=2xnn | SCENE= }} | ||
===STRUCTURE OF NEK2 BOUND TO CCT242430=== | ===STRUCTURE OF NEK2 BOUND TO CCT242430=== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:021366329</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
[[Category: Bayliss, R.]] | [[Category: Bayliss, R.]] | ||
[[Category: Mas-Droux, C.]] | [[Category: Mas-Droux, C.]] | ||
| + | [[Category: Cell cycle]] | ||
| + | [[Category: Centrosome]] | ||
| + | [[Category: Mitosis]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 13:43, 6 February 2013
STRUCTURE OF NEK2 BOUND TO CCT242430
Template:ABSTRACT PUBMED 21366329
About this Structure
2xnn is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Solanki S, Innocenti P, Mas-Droux C, Boxall K, Barillari C, van Montfort RL, Aherne GW, Bayliss R, Hoelder S. Benzimidazole Inhibitors Induce a DFG-Out Conformation of Never in Mitosis Gene A-Related Kinase 2 (Nek2) without Binding to the Back Pocket and Reveal a Nonlinear Structure-Activity Relationship. J Med Chem. 2011 Mar 24;54(6):1626-39. Epub 2011 Mar 2. PMID:21366329 doi:10.1021/jm1011726
