3mxf
From Proteopedia
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{{STRUCTURE_3mxf| PDB=3mxf | SCENE= }} | {{STRUCTURE_3mxf| PDB=3mxf | SCENE= }} | ||
| - | ===Crystal Structure of the first bromodomain of | + | ===Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor JQ1=== |
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==About this Structure== | ==About this Structure== | ||
| - | [[3mxf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[3mxf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MXF OCA]. |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020871596</ref><references group="xtra"/> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Arrowsmith, C H.]] | [[Category: Arrowsmith, C H.]] | ||
[[Category: Bountra, C.]] | [[Category: Bountra, C.]] | ||
| Line 39: | Line 39: | ||
[[Category: SGC, Structural Genomics Consortium.]] | [[Category: SGC, Structural Genomics Consortium.]] | ||
[[Category: Weigelt, J.]] | [[Category: Weigelt, J.]] | ||
| + | [[Category: Betsoff1]] | ||
| + | [[Category: Brd4]] | ||
| + | [[Category: Bromodomain containing protein 4]] | ||
| + | [[Category: Bromodomain-containing protein 4 isoform long]] | ||
| + | [[Category: Cap]] | ||
| + | [[Category: Cell cycle]] | ||
| + | [[Category: Hunk1]] | ||
| + | [[Category: Jq1]] | ||
| + | [[Category: Mcap]] | ||
| + | [[Category: Mitotic chromosome associated protein]] | ||
| + | [[Category: Sgc]] | ||
| + | [[Category: Structural genomics consortium]] | ||
Revision as of 06:56, 28 March 2012
Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor JQ1
Template:ABSTRACT PUBMED 20871596
About this Structure
3mxf is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Filippakopoulos P, Qi J, Picaud S, Shen Y, Smith WB, Fedorov O, Morse EM, Keates T, Hickman TT, Felletar I, Philpott M, Munro S, McKeown MR, Wang Y, Christie AL, West N, Cameron MJ, Schwartz B, Heightman TD, La Thangue N, French CA, Wiest O, Kung AL, Knapp S, Bradner JE. Selective inhibition of BET bromodomains. Nature. 2010 Sep 24. PMID:20871596 doi:10.1038/nature09504
Categories: Homo sapiens | Arrowsmith, C H. | Bountra, C. | Bradner, J E. | Delft, F von. | Edwards, A M. | Fedorov, O. | Felletar, I. | Filippakopoulos, P. | Keates, T. | Knapp, S. | Muniz, J. | Picaud, S. | Qi, J. | SGC, Structural Genomics Consortium. | Weigelt, J. | Betsoff1 | Brd4 | Bromodomain containing protein 4 | Bromodomain-containing protein 4 isoform long | Cap | Cell cycle | Hunk1 | Jq1 | Mcap | Mitotic chromosome associated protein | Sgc | Structural genomics consortium
