This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.

3nax

From Proteopedia

(Difference between revisions)

Jump to: navigation, search

Revision as of 08:21, 6 April 2011

Image:3nax.png

Template:STRUCTURE 3nax

PDK1 in complex with inhibitor MP7

Template:ABSTRACT PUBMED 21118801

About this Structure

3nax is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Nagashima K, Shumway SD, Sathyanarayanan S, Chen AH, Dolinski B, Xu Y, Keilhack H, Nguyen T, Wiznerowicz M, Li L, Lutterbach BA, Chi A, Paweletz C, Allison T, Yan Y, Munshi SK, Klippel A, Kraus M, Bobkova EV, Deshmukh S, Xu Z, Mueller U, Szewczak AA, Pan BS, Richon V, Pollock R, Blume-Jensen P, Northrup A, Andersen JN. Genetic and pharmacological inhibition of PDK1 in cancer cells: characterization of a selective allosteric kinase inhibitor. J Biol Chem. 2011 Feb 25;286(8):6433-48. Epub 2010 Nov 30. PMID:21118801 doi:10.1074/jbc.M110.156463