3qpl

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'''Unreleased structure'''
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[[Image:3qpl.jpg|left|200px]]
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The entry 3qpl is ON HOLD until Paper Publication
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{{STRUCTURE_3qpl| PDB=3qpl | SCENE= }}
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Authors: Carette, X., Willery, E., Hoos, S., Lecat-Guillet, N., Frenois, F., Dirie, B., Villeret, V., England, P., Deprez, B., Locht, C., Willand, N., Baulard, A.
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===G106W mutant of EthR from Mycobacterium tuberculosis===
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Description: G106W mutant of EthR from Mycobacterium tuberculosis
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{{ABSTRACT_PUBMED_22156370}}
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==About this Structure==
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[[3qpl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QPL OCA].
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==Reference==
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<ref group="xtra">PMID:022156370</ref><ref group="xtra">PMID:019412174</ref><ref group="xtra">PMID:020704273</ref><references group="xtra"/>
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Baulard, A.]]
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[[Category: Carette, X.]]
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[[Category: Deprez, B.]]
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[[Category: Dirie, B.]]
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[[Category: England, P.]]
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[[Category: Frenois, F.]]
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[[Category: Hoos, S.]]
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[[Category: Lecat-Guillet, N.]]
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[[Category: Locht, C.]]
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[[Category: Villeret, V.]]
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[[Category: Willand, N.]]
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[[Category: Willery, E.]]
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[[Category: Hth motif]]
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[[Category: Transcription]]
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[[Category: Transcriptional repressor]]

Revision as of 07:22, 28 December 2011

Image:3qpl.jpg

Template:STRUCTURE 3qpl

G106W mutant of EthR from Mycobacterium tuberculosis

Template:ABSTRACT PUBMED 22156370

About this Structure

3qpl is a 1 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

Reference

  • Carette X, Blondiaux N, Willery E, Hoos S, Lecat-Guillet N, Lens Z, Wohlkonig A, Wintjens R, Soror SH, Frenois F, Dirie B, Villeret V, England P, Lippens G, Deprez B, Locht C, Willand N, Baulard AR. Structural activation of the transcriptional repressor EthR from Mycobacterium tuberculosis by single amino acid change mimicking natural and synthetic ligands. Nucleic Acids Res. 2011 Dec 9. PMID:22156370 doi:10.1093/nar/gkr1113
  • Willand N, Dirie B, Carette X, Bifani P, Singhal A, Desroses M, Leroux F, Willery E, Mathys V, Deprez-Poulain R, Delcroix G, Frenois F, Aumercier M, Locht C, Villeret V, Deprez B, Baulard AR. Synthetic EthR inhibitors boost antituberculous activity of ethionamide. Nat Med. 2009 May;15(5):537-44. Epub 2009 May 3. PMID:19412174 doi:10.1038/nm.1950
  • Willand N, Desroses M, Toto P, Dirie B, Lens Z, Villeret V, Rucktooa P, Locht C, Baulard A, Deprez B. Exploring Drug Target Flexibility Using in Situ Click Chemistry: Application to a Mycobacterial Transcriptional Regulator. ACS Chem Biol. 2010 Aug 26. PMID:20704273 doi:10.1021/cb100177g

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