2uz9

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[[Image:2uz9.jpg|left|200px]]<br /><applet load="2uz9" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2uz9.jpg|left|200px]]<br /><applet load="2uz9" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2uz9, resolution 2.30&Aring;" />
caption="2uz9, resolution 2.30&Aring;" />
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'''HUMAN GUANINE DEAMINASE (GUAD) IN COMPLEX WITH ZINC AND ITS PRODUCT XHANTINE.'''<br />
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'''HUMAN GUANINE DEAMINASE (GUAD) IN COMPLEX WITH ZINC AND ITS PRODUCT XANTHINE.'''<br />
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==Disease==
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Known diseases associated with this structure: Charcot-Marie-Tooth disease, mixed axonal and demyelinating type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606598 606598]], Charcot-Marie-Tooth disease, type 2G OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606598 606598]], Charcot-Marie-Tooth disease, type 2K OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606598 606598]], Charcot-Marie-Tooth disease, type 4A OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606598 606598]]
==About this Structure==
==About this Structure==
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2UZ9 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=XAN:'>XAN</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Guanine_deaminase Guanine deaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.3 3.5.4.3] Known structural/functional Site: <scene name='pdbsite=AC1:Xan Binding Site For Chain A'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UZ9 OCA].
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2UZ9 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=XAN:'>XAN</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Guanine_deaminase Guanine deaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.3 3.5.4.3] Known structural/functional Sites: <scene name='pdbsite=AC1:Zn Binding Site For Residue A 1452'>AC1</scene> and <scene name='pdbsite=AC2:Xan Binding Site For Residue A 1453'>AC2</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UZ9 OCA].
[[Category: Guanine deaminase]]
[[Category: Guanine deaminase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: zinc]]
[[Category: zinc]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 23 15:15:31 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 31 11:00:36 2008''

Revision as of 09:00, 31 January 2008

Image:2uz9.jpg

2uz9, resolution 2.30Å

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HUMAN GUANINE DEAMINASE (GUAD) IN COMPLEX WITH ZINC AND ITS PRODUCT XANTHINE.

Disease

Known diseases associated with this structure: Charcot-Marie-Tooth disease, mixed axonal and demyelinating type OMIM:[606598], Charcot-Marie-Tooth disease, type 2G OMIM:[606598], Charcot-Marie-Tooth disease, type 2K OMIM:[606598], Charcot-Marie-Tooth disease, type 4A OMIM:[606598]

About this Structure

2UZ9 is a Single protein structure of sequence from Homo sapiens with and as ligands. Active as Guanine deaminase, with EC number 3.5.4.3 Known structural/functional Sites: and . Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Jan 31 11:00:36 2008

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