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2uz9
From Proteopedia
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[[Image:2uz9.jpg|left|200px]]<br /><applet load="2uz9" size="350" color="white" frame="true" align="right" spinBox="true" | [[Image:2uz9.jpg|left|200px]]<br /><applet load="2uz9" size="350" color="white" frame="true" align="right" spinBox="true" | ||
caption="2uz9, resolution 2.30Å" /> | caption="2uz9, resolution 2.30Å" /> | ||
| - | '''HUMAN GUANINE DEAMINASE (GUAD) IN COMPLEX WITH ZINC AND ITS PRODUCT | + | '''HUMAN GUANINE DEAMINASE (GUAD) IN COMPLEX WITH ZINC AND ITS PRODUCT XANTHINE.'''<br /> |
| + | |||
| + | ==Disease== | ||
| + | Known diseases associated with this structure: Charcot-Marie-Tooth disease, mixed axonal and demyelinating type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606598 606598]], Charcot-Marie-Tooth disease, type 2G OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606598 606598]], Charcot-Marie-Tooth disease, type 2K OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606598 606598]], Charcot-Marie-Tooth disease, type 4A OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606598 606598]] | ||
==About this Structure== | ==About this Structure== | ||
| - | 2UZ9 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=XAN:'>XAN</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Guanine_deaminase Guanine deaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.3 3.5.4.3] Known structural/functional | + | 2UZ9 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=XAN:'>XAN</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Guanine_deaminase Guanine deaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.3 3.5.4.3] Known structural/functional Sites: <scene name='pdbsite=AC1:Zn Binding Site For Residue A 1452'>AC1</scene> and <scene name='pdbsite=AC2:Xan Binding Site For Residue A 1453'>AC2</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UZ9 OCA]. |
[[Category: Guanine deaminase]] | [[Category: Guanine deaminase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: zinc]] | [[Category: zinc]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 31 11:00:36 2008'' |
Revision as of 09:00, 31 January 2008
|
HUMAN GUANINE DEAMINASE (GUAD) IN COMPLEX WITH ZINC AND ITS PRODUCT XANTHINE.
Disease
Known diseases associated with this structure: Charcot-Marie-Tooth disease, mixed axonal and demyelinating type OMIM:[606598], Charcot-Marie-Tooth disease, type 2G OMIM:[606598], Charcot-Marie-Tooth disease, type 2K OMIM:[606598], Charcot-Marie-Tooth disease, type 4A OMIM:[606598]
About this Structure
2UZ9 is a Single protein structure of sequence from Homo sapiens with and as ligands. Active as Guanine deaminase, with EC number 3.5.4.3 Known structural/functional Sites: and . Full crystallographic information is available from OCA.
Page seeded by OCA on Thu Jan 31 11:00:36 2008
Categories: Guanine deaminase | Homo sapiens | Single protein | Arrowsmith, C. | Berglund, H. | Busam, R. | Collins, R. | Dahlgren, L.G. | Edwards, A. | Flodin, S. | Flores, A. | Graslund, S. | Hallberg, B.M. | Hammarstrom, M. | Holmberg-Schiavone, L. | Johansson, I. | Kallas, A. | Karlberg, T. | Kotenyova, T. | Lehtio, L. | Moche, M. | Nordlund, P. | Nyman, T. | Ogg, D. | Persson, C. | Sagemark, J. | Sgc, Structural.Genomics.Consortium. | Stenmark, P. | Sundstrom, M. | Thorsell, A.G. | Van-Den-Berg, S. | Weigelt, J. | Welin, M. | XAN | ZN | Guanine aminohydrolase | Hydrolase | Purine metabolism | Zinc
