3qkd
From Proteopedia
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{{STRUCTURE_3qkd| PDB=3qkd | SCENE= }} | {{STRUCTURE_3qkd| PDB=3qkd | SCENE= }} | ||
===Crystal structure of Bcl-xL in complex with a Quinazoline sulfonamide inhibitor=== | ===Crystal structure of Bcl-xL in complex with a Quinazoline sulfonamide inhibitor=== | ||
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{{ABSTRACT_PUBMED_21366295}} | {{ABSTRACT_PUBMED_21366295}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3qkd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QKD OCA]. | + | [[3qkd]] is a 2 chain structure of [[Bcl-2]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QKD OCA]. |
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| + | ==See Also== | ||
| + | *[[Bcl-2|Bcl-2]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:021366295</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Czabotar, P E.]] | [[Category: Czabotar, P E.]] | ||
[[Category: Smith, B J.]] | [[Category: Smith, B J.]] | ||
| + | [[Category: Apoptosis-inhibitor complex]] | ||
| + | [[Category: Bcl-2 family fold]] | ||
Revision as of 12:18, 27 July 2012
Contents |
Crystal structure of Bcl-xL in complex with a Quinazoline sulfonamide inhibitor
Template:ABSTRACT PUBMED 21366295
About this Structure
3qkd is a 2 chain structure of Bcl-2 with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Sleebs BE, Czabotar PE, Fairbrother WJ, Fairlie WD, Flygare JA, Huang DC, Kersten WJ, Koehler MF, Lessene G, Lowes K, Parisot JP, Smith BJ, Smith ML, Souers AJ, Street IP, Yang H, Baell JB. Quinazoline sulfonamides as dual binders of the proteins B-cell lymphoma 2 and B-cell lymphoma extra long with potent proapoptotic cell-based activity. J Med Chem. 2011 Mar 24;54(6):1914-26. Epub 2011 Mar 2. PMID:21366295 doi:10.1021/jm101596e
