Gramicidin
From Proteopedia
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[[Image:2xdc.png|left|200px|thumb|Crystal Structure of Gramicidin, [[2xdc]]]] | [[Image:2xdc.png|left|200px|thumb|Crystal Structure of Gramicidin, [[2xdc]]]] | ||
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Gramicidin (GCDN) is a polypeptide composed of alternating L- and D-amino acids. It has bactericidal activity and is used as antibiotic. It is produced by the bacteria ''Bacillus brevis''. GCDN S is a cyclic polypeptide. GCDN D is a mixture of GCDN A, B, C. | Gramicidin (GCDN) is a polypeptide composed of alternating L- and D-amino acids. It has bactericidal activity and is used as antibiotic. It is produced by the bacteria ''Bacillus brevis''. GCDN S is a cyclic polypeptide. GCDN D is a mixture of GCDN A, B, C. |
Revision as of 06:43, 14 April 2011
Image:2xdc.png
Crystal Structure of Gramicidin, 2xdc
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Gramicidin (GCDN) is a polypeptide composed of alternating L- and D-amino acids. It has bactericidal activity and is used as antibiotic. It is produced by the bacteria Bacillus brevis. GCDN S is a cyclic polypeptide. GCDN D is a mixture of GCDN A, B, C.
3D Structures of Gramicidin
Gramicidin A
1nt5, 1nt6, 1nrm, 1nru, 1ng8, 1kqe, 1jno, 1jo3, 1jo4, 1mic, 1mag, 1grm - GCDN A – NMR
1tkq - GCDN A + mini-GCDN A – NMR
1av2 - GCDN A + CsCl
1gmk - GCDN A + KCNS
Gramicidin D
2xdc, 1w5u, 1bdw, 1al4, 1alx, 1alz – GCDN D
3lml, 2izq - GCDN D + iodide
1c4d - GCDN D + CsCl