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1uir

From Proteopedia

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[[Image:1uir.png|left|200px]]
 
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{{STRUCTURE_1uir| PDB=1uir | SCENE= }}
{{STRUCTURE_1uir| PDB=1uir | SCENE= }}
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===Crystal Structure of Polyamine Aminopropyltransfease from Thermus thermophilus===
===Crystal Structure of Polyamine Aminopropyltransfease from Thermus thermophilus===
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{{ABSTRACT_PUBMED_21458463}}
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==Function==
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[[http://www.uniprot.org/uniprot/SPEE_THET8 SPEE_THET8]] Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor. Has broad substrate specificity. Is also active with agmatine and norspermidine. Has lower activity with homospermidine, mitsubishine and thermine.<ref>PMID:21458463</ref>
==About this Structure==
==About this Structure==
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[[1uir]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UIR OCA].
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[[1uir]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UIR OCA].
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[[Category: Thermus thermophilus]]
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==Reference==
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<ref group="xtra">PMID:021458463</ref><references group="xtra"/><references/>
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[[Category: Flavobacterium thermophilum yoshida and oshima 1971]]
[[Category: Ganbe, T.]]
[[Category: Ganbe, T.]]
[[Category: Kumasaka, T.]]
[[Category: Kumasaka, T.]]
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[[Category: Sato, T.]]
[[Category: Sato, T.]]
[[Category: Tanaka, N.]]
[[Category: Tanaka, N.]]
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[[Category: Polyamine]]
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[[Category: Riken structural genomics/proteomics initiative]]
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[[Category: Rsgi]]
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[[Category: Spermidien synthase]]
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[[Category: Spermine synthase]]
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[[Category: Structural genomic]]
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[[Category: Transferase]]

Revision as of 06:02, 29 January 2014

Template:STRUCTURE 1uir

Contents

Crystal Structure of Polyamine Aminopropyltransfease from Thermus thermophilus

Template:ABSTRACT PUBMED 21458463

Function

[SPEE_THET8] Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor. Has broad substrate specificity. Is also active with agmatine and norspermidine. Has lower activity with homospermidine, mitsubishine and thermine.[1]

About this Structure

1uir is a 2 chain structure with sequence from "flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971. Full crystallographic information is available from OCA.

Reference

  • Ohnuma M, Ganbe T, Terui Y, Niitsu M, Sato T, Tanaka N, Tamakoshi M, Samejima K, Kumasaka T, Oshima T. Crystal structures and enzymatic properties of a triamine/agmatine aminopropyltransferase from Thermus thermophilus. J Mol Biol. 2011 May 20;408(5):971-86. Epub 2011 Mar 31. PMID:21458463 doi:http://dx.doi.org/10.1016/j.jmb.2011.03.025
  1. Ohnuma M, Ganbe T, Terui Y, Niitsu M, Sato T, Tanaka N, Tamakoshi M, Samejima K, Kumasaka T, Oshima T. Crystal structures and enzymatic properties of a triamine/agmatine aminopropyltransferase from Thermus thermophilus. J Mol Biol. 2011 May 20;408(5):971-86. Epub 2011 Mar 31. PMID:21458463 doi:http://dx.doi.org/10.1016/j.jmb.2011.03.025

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