3qj0
From Proteopedia
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==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:021434688</ref><references group="xtra"/> |
[[Category: Bontoxilysin]] | [[Category: Bontoxilysin]] | ||
[[Category: Clostridium botulinum]] | [[Category: Clostridium botulinum]] |
Revision as of 05:58, 25 May 2011
Crystal Structure of BoNT/A LC complexed with Hydroxamate-based Inhibitor PT-3
Template:ABSTRACT PUBMED 21434688
About this Structure
3qj0 is a 1 chain structure with sequence from Clostridium botulinum. Full crystallographic information is available from OCA.
Reference
- Thompson AA, Jiao GS, Kim S, Thai A, Cregar-Hernandez L, Margosiak SA, Johnson AT, Han GW, O'Malley S, Stevens RC. Structural Characterization of Three Novel Hydroxamate-based Zinc Chelating Inhibitors of the C. botulinum Serotype A Neurotoxin Light Chain Metalloprotease Reveals a Compact Binding Site Resulting from 60/70 Loop Flexibility. Biochemistry. 2011 Mar 24. PMID:21434688 doi:10.1021/bi2001483