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3q36

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[[Image:3q36.jpg|left|200px]]
 
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{{STRUCTURE_3q36| PDB=3q36 | SCENE= }}
{{STRUCTURE_3q36| PDB=3q36 | SCENE= }}
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===Crystal structure of the 4Fe-4S cluster domain of human DNA primase large subunit===
===Crystal structure of the 4Fe-4S cluster domain of human DNA primase large subunit===
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{{ABSTRACT_PUBMED_21346410}}
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==Function==
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[[http://www.uniprot.org/uniprot/PRI2_HUMAN PRI2_HUMAN]] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.
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(as it appears on PubMed at http://www.pubmed.gov), where 21346410 is the PubMed ID number.
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{{ABSTRACT_PUBMED_21346410}}
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==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:21346410</ref><references group="xtra"/>
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<ref group="xtra">PMID:021346410</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Agarkar, V B.]]
[[Category: Agarkar, V B.]]
[[Category: Babayeva, N D.]]
[[Category: Babayeva, N D.]]
[[Category: Tahirov, T H.]]
[[Category: Tahirov, T H.]]
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[[Category: Dna replication]]
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[[Category: Dna-binding]]
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[[Category: Dna-directed rna polymerase]]
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[[Category: Iron-sulfur cluster]]
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[[Category: Metal-binding]]
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[[Category: Nucleotidyltransferase]]
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[[Category: Phosphoprotein]]
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[[Category: Pol alpha]]
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[[Category: Polymerase]]
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[[Category: Primase]]
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[[Category: Primosome]]
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[[Category: Transcription]]
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[[Category: Transferase]]

Revision as of 08:14, 8 May 2013

Template:STRUCTURE 3q36

Contents

Crystal structure of the 4Fe-4S cluster domain of human DNA primase large subunit

Template:ABSTRACT PUBMED 21346410

Function

[PRI2_HUMAN] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.

About this Structure

3q36 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Agarkar VB, Babayeva ND, Pavlov YI, Tahirov TH. Crystal structure of the C-terminal domain of human DNA primase large subunit: Implications for the mechanism of the primase - polymerase alpha switch. Cell Cycle. 2011 Mar 15;10(6). PMID:21346410

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