Phage integrase

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== 3D Structures of phage integrase ==
== 3D Structures of phage integrase ==
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''Update June 2011''
[[3nrw]] – PIN/site-specific recombinase N-terminal – ''Haloarcula marismortui''<br />
[[3nrw]] – PIN/site-specific recombinase N-terminal – ''Haloarcula marismortui''<br />
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[[1p7d]] – λPIN fragment + DNA <br />
[[1p7d]] – λPIN fragment + DNA <br />
[[3bvp]] – PIN catalytic core domain – Lactococcus phage TP101-1<br />
[[3bvp]] – PIN catalytic core domain – Lactococcus phage TP101-1<br />
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[[1aih]] - PIN catalytic core domain – Haemophilus phage HP1
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[[1aih]] - PIN catalytic core domain – Haemophilus phage HP1<br />
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[[2khv]], [[2kj5]] – PIN residues 102-199 – ''Nitrosospira multiformis'' - NMR
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 06:15, 19 June 2011

Image:1z1g.png
Crystal Structure of Enterobacteria phage λ integrase 1z1g

Template:STRUCTURE 1z1g


Phage integrase (PIN) mediate recombination between DNA recognition sequences - the phage attP and the bacterial attB. The Tyrosine family PIN uses a catalytic tyrosine to mediate strand cleavage while the Serine family PIN uses a serine residue. The High-Pathogenicity Island (HPI) is a genomic island essential for virulence of the family of Enterobacteria.

Contents

3D Structures of phage integrase

Update June 2011

3nrw – PIN/site-specific recombinase N-terminal – Haloarcula marismortui
3jtz – PIN arm-type binding domain – Yersinia pestis
3ju0 – HPI PIN arm-type binding domain – Pectobacterium atrosepticum
2kkp – PIN SAM-like domain – Moorella thermoacetica – NMR
2kkv – PIN fragment – Salmonella enterica – NMR
2khq - PIN fragment – Staphylococcus saprophyticus – NMR
2wcc – λPIN DBD+ DNA – Enterobacteria phage λ - NMR
1kjk – λPIN N-terminal - NMR
2oxo, 1z19, 1z1b - λPIN core binding domain + DNA
1ae9 - λPIN catalytic core domain (mutant)
1z1g – λPIN + DNA (Holliday junction)
1p7d – λPIN fragment + DNA
3bvp – PIN catalytic core domain – Lactococcus phage TP101-1
1aih - PIN catalytic core domain – Haemophilus phage HP1
2khv, 2kj5 – PIN residues 102-199 – Nitrosospira multiformis - NMR

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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