3pyi

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[[Image:3pyi.png|left|200px]]
 
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{{STRUCTURE_3pyi| PDB=3pyi | SCENE= }}
{{STRUCTURE_3pyi| PDB=3pyi | SCENE= }}
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===Structure of the N-terminal domain of C. elegans SAS-6===
===Structure of the N-terminal domain of C. elegans SAS-6===
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{{ABSTRACT_PUBMED_21277013}}
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==Function==
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[[http://www.uniprot.org/uniprot/SAS6_CAEEL SAS6_CAEEL]] Required for centrosome duplication. Participates in centriole assembly.<ref>PMID:15572125</ref> <ref>PMID:15665853</ref>
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{{ABSTRACT_PUBMED_21277013}}
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==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:21277013</ref><references group="xtra"/>
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<ref group="xtra">PMID:021277013</ref><references group="xtra"/><references/>
[[Category: Caenorhabditis elegans]]
[[Category: Caenorhabditis elegans]]
[[Category: Steinmetz, M O.]]
[[Category: Steinmetz, M O.]]
[[Category: Vakonakis, I.]]
[[Category: Vakonakis, I.]]
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[[Category: Alpha-beta protein]]
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[[Category: Beta-sandwich]]
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[[Category: Centriolar]]
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[[Category: Cytoplasmic]]
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[[Category: Dimer]]
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[[Category: Structural protein]]

Revision as of 08:23, 8 May 2013

Template:STRUCTURE 3pyi

Contents

Structure of the N-terminal domain of C. elegans SAS-6

Template:ABSTRACT PUBMED 21277013

Function

[SAS6_CAEEL] Required for centrosome duplication. Participates in centriole assembly.[1] [2]

About this Structure

3pyi is a 2 chain structure with sequence from Caenorhabditis elegans. Full crystallographic information is available from OCA.

Reference

  • Kitagawa D, Vakonakis I, Olieric N, Hilbert M, Keller D, Olieric V, Bortfeld M, Erat MC, Fluckiger I, Gonczy P, Steinmetz MO. Structural basis of the 9-fold symmetry of centrioles. Cell. 2011 Feb 4;144(3):364-75. PMID:21277013 doi:10.1016/j.cell.2011.01.008
  1. Dammermann A, Muller-Reichert T, Pelletier L, Habermann B, Desai A, Oegema K. Centriole assembly requires both centriolar and pericentriolar material proteins. Dev Cell. 2004 Dec;7(6):815-29. PMID:15572125 doi:S1534580704003806
  2. Leidel S, Delattre M, Cerutti L, Baumer K, Gonczy P. SAS-6 defines a protein family required for centrosome duplication in C. elegans and in human cells. Nat Cell Biol. 2005 Feb;7(2):115-25. PMID:15665853 doi:ncb1220

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