3pyi
From Proteopedia
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{{STRUCTURE_3pyi| PDB=3pyi | SCENE= }} | {{STRUCTURE_3pyi| PDB=3pyi | SCENE= }} | ||
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===Structure of the N-terminal domain of C. elegans SAS-6=== | ===Structure of the N-terminal domain of C. elegans SAS-6=== | ||
+ | {{ABSTRACT_PUBMED_21277013}} | ||
- | + | ==Function== | |
- | + | [[http://www.uniprot.org/uniprot/SAS6_CAEEL SAS6_CAEEL]] Required for centrosome duplication. Participates in centriole assembly.<ref>PMID:15572125</ref> <ref>PMID:15665853</ref> | |
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==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:021277013</ref><references group="xtra"/><references/> |
[[Category: Caenorhabditis elegans]] | [[Category: Caenorhabditis elegans]] | ||
[[Category: Steinmetz, M O.]] | [[Category: Steinmetz, M O.]] | ||
[[Category: Vakonakis, I.]] | [[Category: Vakonakis, I.]] | ||
+ | [[Category: Alpha-beta protein]] | ||
+ | [[Category: Beta-sandwich]] | ||
+ | [[Category: Centriolar]] | ||
+ | [[Category: Cytoplasmic]] | ||
+ | [[Category: Dimer]] | ||
+ | [[Category: Structural protein]] |
Revision as of 08:23, 8 May 2013
Contents |
Structure of the N-terminal domain of C. elegans SAS-6
Template:ABSTRACT PUBMED 21277013
Function
[SAS6_CAEEL] Required for centrosome duplication. Participates in centriole assembly.[1] [2]
About this Structure
3pyi is a 2 chain structure with sequence from Caenorhabditis elegans. Full crystallographic information is available from OCA.
Reference
- Kitagawa D, Vakonakis I, Olieric N, Hilbert M, Keller D, Olieric V, Bortfeld M, Erat MC, Fluckiger I, Gonczy P, Steinmetz MO. Structural basis of the 9-fold symmetry of centrioles. Cell. 2011 Feb 4;144(3):364-75. PMID:21277013 doi:10.1016/j.cell.2011.01.008
- ↑ Dammermann A, Muller-Reichert T, Pelletier L, Habermann B, Desai A, Oegema K. Centriole assembly requires both centriolar and pericentriolar material proteins. Dev Cell. 2004 Dec;7(6):815-29. PMID:15572125 doi:S1534580704003806
- ↑ Leidel S, Delattre M, Cerutti L, Baumer K, Gonczy P. SAS-6 defines a protein family required for centrosome duplication in C. elegans and in human cells. Nat Cell Biol. 2005 Feb;7(2):115-25. PMID:15665853 doi:ncb1220