2x6e
From Proteopedia
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[[Image:2x6e.png|left|200px]] | [[Image:2x6e.png|left|200px]] | ||
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{{STRUCTURE_2x6e| PDB=2x6e | SCENE= }} | {{STRUCTURE_2x6e| PDB=2x6e | SCENE= }} | ||
===AURORA-A BOUND TO AN INHIBITOR=== | ===AURORA-A BOUND TO AN INHIBITOR=== | ||
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==Reference== | ==Reference== | ||
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[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
[[Category: Bayliss, R.]] | [[Category: Bayliss, R.]] | ||
[[Category: Kosmopoulou, M.]] | [[Category: Kosmopoulou, M.]] | ||
| + | [[Category: Cell cycle]] | ||
| + | [[Category: Mitosis]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 15:16, 27 February 2013
AURORA-A BOUND TO AN INHIBITOR
Template:ABSTRACT PUBMED 20565112
About this Structure
2x6e is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Bavetsias V, Large JM, Sun C, Bouloc N, Kosmopoulou M, Matteucci M, Wilsher NE, Martins V, Reynisson J, Atrash B, Faisal A, Urban F, Valenti M, de Haven Brandon A, Box G, Raynaud FI, Workman P, Eccles SA, Bayliss R, Blagg J, Linardopoulos S, McDonald E. Imidazo[4,5-b]pyridine Derivatives As Inhibitors of Aurora Kinases: Lead Optimization Studies toward the Identification of an Orally Bioavailable Preclinical Development Candidate. J Med Chem. 2010 Jun 21. PMID:20565112 doi:10.1021/jm100262j
