3ri1

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'''Unreleased structure'''
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[[Image:3ri1.jpg|left|200px]]
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The entry 3ri1 is ON HOLD
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{{STRUCTURE_3ri1| PDB=3ri1 | SCENE= }}
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Authors: Eathiraj, S., Palma, R., Hirschi, M., Volckova, E., Nakuci, E., Castro, J., Chen, C.R., Chan, T.C., France, D.S., Ashwell, M.A.
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===Crystal structure of the catalytic domain of FGFR2 kinase in complex with ARQ 069===
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Description: Crystal structure of the catalytic domain of FGFR2 kinase
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{{ABSTRACT_PUBMED_21454610}}
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==About this Structure==
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[[3ri1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RI1 OCA].
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==Reference==
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<ref group="xtra">PMID:021454610</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Receptor protein-tyrosine kinase]]
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[[Category: Ashwell, M A.]]
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[[Category: Castro, J.]]
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[[Category: Chan, T C.]]
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[[Category: Chen, C R.]]
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[[Category: Eathiraj, S.]]
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[[Category: France, D S.]]
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[[Category: Hirschi, M.]]
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[[Category: Nakuci, E.]]
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[[Category: Palma, R.]]
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[[Category: Volckova, E.]]

Revision as of 06:50, 4 May 2011

Image:3ri1.jpg

Template:STRUCTURE 3ri1

Crystal structure of the catalytic domain of FGFR2 kinase in complex with ARQ 069

Template:ABSTRACT PUBMED 21454610

About this Structure

3ri1 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Eathiraj S, Palma R, Hirschi M, Volckova E, Nakuci E, Castro J, Chen CR, Chan TC, France DS, Ashwell MA. A novel mode of protein kinase inhibition exploiting hydrophobic motifs of auto-inhibited kinases: discovery of ATP independent inhibitors of fibroblast growth factor receptor (FGFR). J Biol Chem. 2011 Mar 24. PMID:21454610 doi:10.1074/jbc.M110.213736

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OCA

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