2xx8
From Proteopedia
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Revision as of 07:16, 27 April 2011
CRYSTAL STRUCTURE OF N,N-DIMETHYL-4-(3-(TRIFLUOROMETHYL)-4, 5,6,7-TETRAHYDRO-1H-INDAZOL-1-YL)BENZAMIDE IN COMPLEX WITH THE LIGAND BINDING DOMAIN OF THE RAT GLUA2 RECEPTOR AND GLUTAMATE AT 2.2A RESOLUTION.
Template:ABSTRACT PUBMED 21128618
About this Structure
2xx8 is a 3 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
Reference
- Ward SE, Harries M, Aldegheri L, Austin NE, Ballantine S, Ballini E, Bradley DM, Bax BD, Clarke BP, Harris AJ, Harrison SA, Melarange RA, Mookherjee C, Mosley J, Dal Negro G, Oliosi B, Smith KJ, Thewlis KM, Woollard PM, Yusaf SP. Integration of Lead Optimization with Crystallography for a Membrane-Bound Ion Channel Target: Discovery of a New Class of AMPA Receptor Positive Allosteric Modulators. J Med Chem. 2010 Dec 3. PMID:21128618 doi:10.1021/jm100679e
Categories: Rattus norvegicus | Aldegheri, L. | Austin, N E. | Ballantine, S. | Ballini, E. | Bax, B D. | Bradley, D M. | Clarke, B P. | Dalnegro, G. | Harries, M. | Harris, A J. | Harrison, S A. | Melarange, R A. | Mookherjee, C. | Mosley, J. | Oliosi, B. | Smith, K J. | Thewlis, K M. | Ward, S E. | Woollard, P M. | Yusaf, S P.
