2yak

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{{STRUCTURE_2yak| PDB=2yak | SCENE= }}
{{STRUCTURE_2yak| PDB=2yak | SCENE= }}
===STRUCTURE OF DEATH-ASSOCIATED PROTEIN KINASE 1 (DAPK1) IN COMPLEX WITH A RUTHENIUM OCTASPORINE LIGAND (OSV)===
===STRUCTURE OF DEATH-ASSOCIATED PROTEIN KINASE 1 (DAPK1) IN COMPLEX WITH A RUTHENIUM OCTASPORINE LIGAND (OSV)===
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{{ABSTRACT_PUBMED_21446733}}
{{ABSTRACT_PUBMED_21446733}}
==About this Structure==
==About this Structure==
[[2yak]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YAK OCA].
[[2yak]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YAK OCA].
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==See Also==
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*[[Death-associated protein kinase|Death-associated protein kinase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:21446733</ref><ref group="xtra">PMID:18973295</ref><ref group="xtra">PMID:19035373</ref><references group="xtra"/>
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<ref group="xtra">PMID:021446733</ref><ref group="xtra">PMID:018973295</ref><ref group="xtra">PMID:019035373</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Meggers, E.]]
[[Category: Meggers, E.]]
[[Category: Wilbuer, A.]]
[[Category: Wilbuer, A.]]
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[[Category: Kinase inhibitor]]
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[[Category: Octahedral ruthenium inhibitory complex]]
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[[Category: Transferase]]

Revision as of 10:52, 20 October 2012

Image:2yak.png

Template:STRUCTURE 2yak

Contents

STRUCTURE OF DEATH-ASSOCIATED PROTEIN KINASE 1 (DAPK1) IN COMPLEX WITH A RUTHENIUM OCTASPORINE LIGAND (OSV)

Template:ABSTRACT PUBMED 21446733

About this Structure

2yak is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Feng L, Geisselbrecht Y, Blanck S, Wilbuer A, Atilla-Gokcumen GE, Filippakopoulos P, Kraling K, Celik MA, Harms K, Maksimoska J, Marmorstein R, Frenking G, Knapp S, Essen LO, Meggers E. Structurally Sophisticated Octahedral Metal Complexes as Highly Selective Protein Kinase Inhibitors. J Am Chem Soc. 2011 Apr 20;133(15):5976-5986. Epub 2011 Mar 29. PMID:21446733 doi:10.1021/ja1112996
  • Maksimoska J, Feng L, Harms K, Yi C, Kissil J, Marmorstein R, Meggers E. Targeting large kinase active site with rigid, bulky octahedral ruthenium complexes. J Am Chem Soc. 2008 Nov 26;130(47):15764-5. PMID:18973295 doi:10.1021/ja805555a
  • Atilla-Gokcumen GE, Pagano N, Streu C, Maksimoska J, Filippakopoulos P, Knapp S, Meggers E. Extremely tight binding of a ruthenium complex to glycogen synthase kinase 3. Chembiochem. 2008 Dec 15;9(18):2933-6. PMID:19035373 doi:10.1002/cbic.200800489

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