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3n59
From Proteopedia
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| - | [[Image:3n59.png|left|200px]] | ||
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{{STRUCTURE_3n59| PDB=3n59 | SCENE= }} | {{STRUCTURE_3n59| PDB=3n59 | SCENE= }} | ||
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===Type II dehydroquinase from Mycobacterium Tuberculosis complexed with 3-dehydroshikimate=== | ===Type II dehydroquinase from Mycobacterium Tuberculosis complexed with 3-dehydroshikimate=== | ||
| + | {{ABSTRACT_PUBMED_21410435}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/AROQ_MYCTU AROQ_MYCTU]] Catalyzes a trans-dehydration via an enolate intermediate (By similarity).[HAMAP-Rule:MF_00169] | |
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==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:021410435</ref><references group="xtra"/> | + | <ref group="xtra">PMID:021410435</ref><references group="xtra"/><references/> |
[[Category: 3-dehydroquinate dehydratase]] | [[Category: 3-dehydroquinate dehydratase]] | ||
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
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[[Category: Snee, W C.]] | [[Category: Snee, W C.]] | ||
[[Category: TBSGC, TB Structural Genomics Consortium.]] | [[Category: TBSGC, TB Structural Genomics Consortium.]] | ||
| + | [[Category: 3-dehydroshikimate]] | ||
| + | [[Category: Aromatic amino acid biosynthesis]] | ||
| + | [[Category: Dehydratase]] | ||
| + | [[Category: Drug target]] | ||
| + | [[Category: Lyase]] | ||
| + | [[Category: Shikimate pathway]] | ||
| + | [[Category: Structural genomic]] | ||
| + | [[Category: Tb structural genomics consortium]] | ||
| + | [[Category: Tbsgc]] | ||
| + | [[Category: Tuberculosis]] | ||
Revision as of 20:44, 17 April 2013
Contents |
Type II dehydroquinase from Mycobacterium Tuberculosis complexed with 3-dehydroshikimate
Template:ABSTRACT PUBMED 21410435
Function
[AROQ_MYCTU] Catalyzes a trans-dehydration via an enolate intermediate (By similarity).[HAMAP-Rule:MF_00169]
About this Structure
3n59 is a 24 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.
Reference
- Dias MV, Snee WC, Bromfield KM, Payne R, Palaninathan SK, Ciulli A, Howard NI, Abell C, Sacchettini JC, Blundell TL. Structural investigation of inhibitor designs targeting 3-dehydroquinate dehydratase from the shikimate pathway of Mycobacterium tuberculosis. Biochem J. 2011 Mar 17. PMID:21410435 doi:10.1042/BJ20110002
Categories: 3-dehydroquinate dehydratase | Mycobacterium tuberculosis | Abell, C. | Blundell, T L. | Bromfield, K M. | Ciulli, A. | Dias, M V.B. | Howard, N I. | Palaninathan, S K. | Payne, R. | Sacchettini, J C. | Snee, W C. | TBSGC, TB Structural Genomics Consortium. | 3-dehydroshikimate | Aromatic amino acid biosynthesis | Dehydratase | Drug target | Lyase | Shikimate pathway | Structural genomic | Tb structural genomics consortium | Tbsgc | Tuberculosis
