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3pxj
From Proteopedia
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{{STRUCTURE_3pxj| PDB=3pxj | SCENE= }} | {{STRUCTURE_3pxj| PDB=3pxj | SCENE= }} | ||
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===Tandem Ig repeats of Dlar=== | ===Tandem Ig repeats of Dlar=== | ||
| + | {{ABSTRACT_PUBMED_21402080}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/LAR_DROME LAR_DROME]] Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase). It controls motor axon guidance.<ref>PMID:2554325</ref> <ref>PMID:8598047</ref> | |
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==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:021402080</ref><references group="xtra"/> | + | <ref group="xtra">PMID:021402080</ref><references group="xtra"/><references/> |
[[Category: Drosophila melanogaster]] | [[Category: Drosophila melanogaster]] | ||
[[Category: Protein-tyrosine-phosphatase]] | [[Category: Protein-tyrosine-phosphatase]] | ||
[[Category: Biersmith, B H.]] | [[Category: Biersmith, B H.]] | ||
[[Category: Bouyain, S.]] | [[Category: Bouyain, S.]] | ||
| + | [[Category: Cell adhesion]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Ig domain]] | ||
| + | [[Category: Receptor protein tyrosine phosphatase]] | ||
Revision as of 08:06, 8 May 2013
Contents |
Tandem Ig repeats of Dlar
Template:ABSTRACT PUBMED 21402080
Function
[LAR_DROME] Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase). It controls motor axon guidance.[1] [2]
About this Structure
3pxj is a 4 chain structure with sequence from Drosophila melanogaster. Full crystallographic information is available from OCA.
Reference
- Biersmith BH, Hammel M, Geisbrecht ER, Bouyain S. The Immunoglobulin-like Domains 1 and 2 of the Protein Tyrosine Phosphatase LAR Adopt an Unusual Horseshoe-like Conformation. J Mol Biol. 2011 May 13;408(4):616-27. Epub 2011 Mar 21. PMID:21402080 doi:10.1016/j.jmb.2011.03.013
- ↑ Streuli M, Krueger NX, Tsai AY, Saito H. A family of receptor-linked protein tyrosine phosphatases in humans and Drosophila. Proc Natl Acad Sci U S A. 1989 Nov;86(22):8698-702. PMID:2554325
- ↑ Krueger NX, Van Vactor D, Wan HI, Gelbart WM, Goodman CS, Saito H. The transmembrane tyrosine phosphatase DLAR controls motor axon guidance in Drosophila. Cell. 1996 Feb 23;84(4):611-22. PMID:8598047
