238d
From Proteopedia
(New page: 200px<br /><applet load="238d" size="350" color="white" frame="true" align="right" spinBox="true" caption="238d, resolution 2.000Å" /> '''CRYSTAL STRUCTURE O...) |
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==Overview== | ==Overview== | ||
| - | The crystal structure of the DNA decamer d(AGGBrCATGCCT) has been | + | The crystal structure of the DNA decamer d(AGGBrCATGCCT) has been determined to a resolution of 2.0 A and R factor of 19.6%. Crystals of d(AGGBrCATGCCT) were grown in the presence of cobalt hexammine but no cobalt hexammine ions are bound to the DNA structure. This contrasts with the recently determined crystal structure of d(AGGCATGCCT) which has a similar DNA conformation and cobalt hexammine ions bound directly to the DNA. Comparison with the structure of d(AGGCATGCCT) and appreciation of the crystal packing of this sequence leads to an understanding of how cobalt hexammine binding to DNA occurs and its role in determining DNA conformation. |
==About this Structure== | ==About this Structure== | ||
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Crystal structure of d(AGGBrCATGCCT): implications for cobalt hexammine binding to DNA., Nunn CM, J Biomol Struct Dyn. 1996 Aug;14(1):49-55. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=8877561 8877561] | Crystal structure of d(AGGBrCATGCCT): implications for cobalt hexammine binding to DNA., Nunn CM, J Biomol Struct Dyn. 1996 Aug;14(1):49-55. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=8877561 8877561] | ||
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
| - | [[Category: Nunn, C | + | [[Category: Nunn, C M.]] |
[[Category: a-dna]] | [[Category: a-dna]] | ||
[[Category: base triplet]] | [[Category: base triplet]] | ||
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[[Category: flipped-out bases]] | [[Category: flipped-out bases]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:21:33 2008'' |
Revision as of 14:21, 21 February 2008
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CRYSTAL STRUCTURE OF THE DNA DECAMER D(AGG(BR)CATGCCT): COMPARISON WITH D(AGGCATGCCT) AND IMPLICATIONS FOR COBALT HEXAMMINE BINDING TO DNA
Overview
The crystal structure of the DNA decamer d(AGGBrCATGCCT) has been determined to a resolution of 2.0 A and R factor of 19.6%. Crystals of d(AGGBrCATGCCT) were grown in the presence of cobalt hexammine but no cobalt hexammine ions are bound to the DNA structure. This contrasts with the recently determined crystal structure of d(AGGCATGCCT) which has a similar DNA conformation and cobalt hexammine ions bound directly to the DNA. Comparison with the structure of d(AGGCATGCCT) and appreciation of the crystal packing of this sequence leads to an understanding of how cobalt hexammine binding to DNA occurs and its role in determining DNA conformation.
About this Structure
238D is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.
Reference
Crystal structure of d(AGGBrCATGCCT): implications for cobalt hexammine binding to DNA., Nunn CM, J Biomol Struct Dyn. 1996 Aug;14(1):49-55. PMID:8877561
Page seeded by OCA on Thu Feb 21 16:21:33 2008
