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3rcq
From Proteopedia
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{{STRUCTURE_3rcq| PDB=3rcq | SCENE= }} | {{STRUCTURE_3rcq| PDB=3rcq | SCENE= }} | ||
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===Crystal structure of human aspartate beta-hydroxylase isoform a=== | ===Crystal structure of human aspartate beta-hydroxylase isoform a=== | ||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/ASPH_HUMAN ASPH_HUMAN]] Isoform 1: specifically hydroxylates an Asp or Asn residue in certain epidermal growth factor-like (EGF) domains of a number of proteins.<ref>PMID:22586105</ref> Isoform 8: membrane-bound Ca(2+)-sensing protein, which is a structural component of the ER-plasma membrane junctions. Isoform 8 regulates the activity of Ca(+2) released-activated Ca(+2) (CRAC) channels in T-cells.<ref>PMID:22586105</ref> | ||
==About this Structure== | ==About this Structure== | ||
[[3rcq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RCQ OCA]. | [[3rcq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RCQ OCA]. | ||
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| + | ==Reference== | ||
| + | <references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Peptide-aspartate beta-dioxygenase]] | [[Category: Peptide-aspartate beta-dioxygenase]] | ||
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[[Category: SGC, Structural Genomics Consortium.]] | [[Category: SGC, Structural Genomics Consortium.]] | ||
[[Category: Weigelt, J.]] | [[Category: Weigelt, J.]] | ||
| + | [[Category: Aspartate beta-hydroxylase isoform some]] | ||
| + | [[Category: Human]] | ||
| + | [[Category: Oxidoreductase]] | ||
| + | [[Category: Sgc]] | ||
| + | [[Category: Structural genomic]] | ||
| + | [[Category: Structural genomics consortium]] | ||
Revision as of 08:10, 16 May 2013
Contents |
Crystal structure of human aspartate beta-hydroxylase isoform a
Function
[ASPH_HUMAN] Isoform 1: specifically hydroxylates an Asp or Asn residue in certain epidermal growth factor-like (EGF) domains of a number of proteins.[1] Isoform 8: membrane-bound Ca(2+)-sensing protein, which is a structural component of the ER-plasma membrane junctions. Isoform 8 regulates the activity of Ca(+2) released-activated Ca(+2) (CRAC) channels in T-cells.[2]
About this Structure
3rcq is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- ↑ Srikanth S, Jew M, Kim KD, Yee MK, Abramson J, Gwack Y. Junctate is a Ca2+-sensing structural component of Orai1 and stromal interaction molecule 1 (STIM1). Proc Natl Acad Sci U S A. 2012 May 29;109(22):8682-7. doi:, 10.1073/pnas.1200667109. Epub 2012 May 14. PMID:22586105 doi:10.1073/pnas.1200667109
- ↑ Srikanth S, Jew M, Kim KD, Yee MK, Abramson J, Gwack Y. Junctate is a Ca2+-sensing structural component of Orai1 and stromal interaction molecule 1 (STIM1). Proc Natl Acad Sci U S A. 2012 May 29;109(22):8682-7. doi:, 10.1073/pnas.1200667109. Epub 2012 May 14. PMID:22586105 doi:10.1073/pnas.1200667109
Categories: Homo sapiens | Peptide-aspartate beta-dioxygenase | Allerston, C K. | Arrowsmith, C H. | Bountra, C. | Bray, J. | Chaikuad, A. | Delft, F von. | Edwards, A. | Gileadi, O. | Hozjan, V. | Kavanagh, K. | Kochan, G. | Krojer, T. | Muniz, J R. | Oppermann, U. | Pilka, E. | SGC, Structural Genomics Consortium. | Weigelt, J. | Aspartate beta-hydroxylase isoform some | Human | Oxidoreductase | Sgc | Structural genomic | Structural genomics consortium
