3pj8

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[[Image:3pj8.png|left|200px]]
[[Image:3pj8.png|left|200px]]
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{{STRUCTURE_3pj8| PDB=3pj8 | SCENE= }}
{{STRUCTURE_3pj8| PDB=3pj8 | SCENE= }}
===Structure of CDK2 in complex with a Pyrazolo[4,3-d]pyrimidine Bioisostere of Roscovitine.===
===Structure of CDK2 in complex with a Pyrazolo[4,3-d]pyrimidine Bioisostere of Roscovitine.===
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{{ABSTRACT_PUBMED_21417417}}
{{ABSTRACT_PUBMED_21417417}}
==About this Structure==
==About this Structure==
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[[3pj8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PJ8 OCA].
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[[3pj8]] is a 1 chain structure of [[Cell Division Protein Kinase 2]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PJ8 OCA].
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==See Also==
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*[[Cell Division Protein Kinase 2|Cell Division Protein Kinase 2]]
==Reference==
==Reference==
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[[Category: Voller, J.]]
[[Category: Voller, J.]]
[[Category: Walkinshaw, M D.]]
[[Category: Walkinshaw, M D.]]
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[[Category: Cell division]]
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[[Category: Cyclin]]
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[[Category: Mitosis]]
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[[Category: Phosphorylation]]
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[[Category: Transferase-transferase inhibitor complex]]

Revision as of 03:41, 26 July 2012

Template:STRUCTURE 3pj8

Contents

Structure of CDK2 in complex with a Pyrazolo[4,3-d]pyrimidine Bioisostere of Roscovitine.

Template:ABSTRACT PUBMED 21417417

About this Structure

3pj8 is a 1 chain structure of Cell Division Protein Kinase 2 with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Jorda R, Havlicek L, McNae IW, Walkinshaw MD, Voller J, Sturc A, Navratilova J, Kuzma M, Mistrik M, Bartek J, Strnad M, Krystof V. Pyrazolo[4,3-d]pyrimidine Bioisostere of Roscovitine: Evaluation of a Novel Selective Inhibitor of Cyclin-dependent Kinases with Antiproliferative Activity. J Med Chem. 2011 Mar 21. PMID:21417417 doi:10.1021/jm200064p

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