3q01

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Revision as of 06:02, 18 May 2011

Template:STRUCTURE 3q01

A conformational switch regulates human p53 DNA binding off-rates

Template:ABSTRACT PUBMED 21522129

About this Structure

3q01 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Petty TJ, Emamzadah S, Costantino L, Petkova I, Stavridi ES, Saven JG, Vauthey E, Halazonetis TD. An induced fit mechanism regulates p53 DNA binding kinetics to confer sequence specificity. EMBO J. 2011 Apr 26. PMID:21522129 doi:10.1038/emboj.2011.127