2b7g
From Proteopedia
(New page: 200px<br /><applet load="2b7g" size="350" color="white" frame="true" align="right" spinBox="true" caption="2b7g" /> '''Structure of the Smaug Recognition RNA Eleme...) |
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==Overview== | ==Overview== | ||
| - | The putative yeast post-transcriptional regulator Vts1p and its related | + | The putative yeast post-transcriptional regulator Vts1p and its related protein Smaug, from Drosophila melanogaster, each use a sterile alpha motif (SAM) domain to bind an RNA hairpin termed the Smaug recognition element (SRE). Here, we present the NMR structures of the Vts1p-SRE complex and the free SRE. Structural highlights include the direct recognition of a guanine base and the formation or stabilization of a base pair in the SRE loop. |
==About this Structure== | ==About this Structure== | ||
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RNA recognition by the Vts1p SAM domain., Johnson PE, Donaldson LW, Nat Struct Mol Biol. 2006 Feb;13(2):177-8. Epub 2006 Jan 22. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16429155 16429155] | RNA recognition by the Vts1p SAM domain., Johnson PE, Donaldson LW, Nat Struct Mol Biol. 2006 Feb;13(2):177-8. Epub 2006 Jan 22. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16429155 16429155] | ||
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
| - | [[Category: Donaldson, L | + | [[Category: Donaldson, L W.]] |
| - | [[Category: Johnson, P | + | [[Category: Johnson, P E.]] |
[[Category: protein-rna complex]] | [[Category: protein-rna complex]] | ||
[[Category: rna]] | [[Category: rna]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:34:56 2008'' |
Revision as of 14:34, 21 February 2008
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Structure of the Smaug Recognition RNA Element
Overview
The putative yeast post-transcriptional regulator Vts1p and its related protein Smaug, from Drosophila melanogaster, each use a sterile alpha motif (SAM) domain to bind an RNA hairpin termed the Smaug recognition element (SRE). Here, we present the NMR structures of the Vts1p-SRE complex and the free SRE. Structural highlights include the direct recognition of a guanine base and the formation or stabilization of a base pair in the SRE loop.
About this Structure
2B7G is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.
Reference
RNA recognition by the Vts1p SAM domain., Johnson PE, Donaldson LW, Nat Struct Mol Biol. 2006 Feb;13(2):177-8. Epub 2006 Jan 22. PMID:16429155
Page seeded by OCA on Thu Feb 21 16:34:56 2008
