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3q05

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{{STRUCTURE_3q05| PDB=3q05 | SCENE= }}
{{STRUCTURE_3q05| PDB=3q05 | SCENE= }}
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===A conformational switch regulates human p53 DNA binding off-rates===
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===An induced fit mechanism regulates p53 DNA binding kinetics to confer sequence specificity===

Revision as of 04:27, 8 June 2011

Image:3q05.png

Template:STRUCTURE 3q05

An induced fit mechanism regulates p53 DNA binding kinetics to confer sequence specificity

Template:ABSTRACT PUBMED 21522129

About this Structure

3q05 is a 6 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Petty TJ, Emamzadah S, Costantino L, Petkova I, Stavridi ES, Saven JG, Vauthey E, Halazonetis TD. An induced fit mechanism regulates p53 DNA binding kinetics to confer sequence specificity. EMBO J. 2011 Apr 26. PMID:21522129 doi:10.1038/emboj.2011.127

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OCA

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