User:Meng Han Liu/Sandbox 1
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| + | ==Introduction== | ||
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| + | In prokaryotes such as [http://en.wikipedia.org/wiki/E.coli ''E. coli''] and [http://en.wikipedia.org/wiki/B._subtilis ''B. subtilis''], chromosomal DNA exists in a circular fashion whereby [[DNA Replication, Transcription and Translation#DNA replication|DNA replication]] takes place at a common [http://en.wikipedia.org/wiki/Origin_of_replication#Prokaryotic origin] (''oriC'') <ref>Duggin, I.G. and S.D. Bell, Termination Structures in the Escherichia coli Chromosome Replication Fork Trap. Journal of Molecular Biology, 2009. 387(3): p. 532-539</ref>. Two replication forks move bidirectionally from ''oriC'' to replicate DNA until they meet, and the forks fuse with one another to form two circular daughter chromosomes <ref>Wake, R.G. and G.F. King, A tale of two terminators: crystal structures sharpen the debate on DNA replication fork arrest mechanisms. Structure, 1997. 5: p. 1-5</ref>. | ||
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| + | ==References== | ||
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Revision as of 13:52, 19 May 2011
Introduction
In prokaryotes such as E. coli and B. subtilis, chromosomal DNA exists in a circular fashion whereby DNA replication takes place at a common origin (oriC) [1]. Two replication forks move bidirectionally from oriC to replicate DNA until they meet, and the forks fuse with one another to form two circular daughter chromosomes [2].
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References
- ↑ Duggin, I.G. and S.D. Bell, Termination Structures in the Escherichia coli Chromosome Replication Fork Trap. Journal of Molecular Biology, 2009. 387(3): p. 532-539
- ↑ Wake, R.G. and G.F. King, A tale of two terminators: crystal structures sharpen the debate on DNA replication fork arrest mechanisms. Structure, 1997. 5: p. 1-5
